Tai Chi Quan Improving Blood Glucose, Blood Lipid, and Quality of Life in Patients With Type 2 Diabetes
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Hemoglobin
研究概览
简要总结
In this study, the hypothesis that the 12-week Tai Chi Quan training would have better control of blood sugar, biochemistry profile, and also better quality of life and activity of autonomic nerve system (ANS). The subjects were randomize assigned to either Tai Chi group or control group. The outcome measures before and after 12-week intervention include basic demographic characteristics, HbA1c, fasting blood glucose(FBG), triglycerides (TG), high and low density lipoprotein (HDL, LDL), creatinine(Cr), eGFR, GPT, ACR, quality of life, and activity of automatic nerve system.
详细描述
In this study, the hypothesis that the 12-week Tai Chi Quan training would have better control of blood sugar, biochemistry index, and also better quality of life and activity of automatic nerve system. In the study, type 2 diabetes mellitus(T2DM) patients will be recruited as subjects. The subjects were randomized to either Tai Chi group or control group. Tai Chi group would take Tai Chi Quan training for 1hr, twice a week for 12 weeks. There were 10-minute warm-up, 40-minute Tai Chi lesson, and 10-minute cool-down exercise in the training. In this study, the 1st section of Yang style 108 form is chosen for the experiment group. Both group were given diabetic patients care education and the exercise recording book for encouraging the daily exercise habits. The outcome measures before and after 12-week intervention include basic demographic characteristics, HbA1c, fasting blood glucose, triglycerides, high and low density lipid, creatinine, eGFR, GPT, ACR, quality of life, and activity of automatic nerve system.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •40~80 years old
- •Diagnosed type 2 diabetes mellitus, and without changing dietary pattern and medical treatment for blood glucose or blood lipid.
- •Consciousness clear and is voluntary to attend the project and with the agreement.
- •The functional movement ability is independent
排除标准
- •Pregnant or plan to be pregnant in six months, and breast feeding.
- •Severe complication in six months such as myocardial infarction, stroke, severe traumatic injury, major surgery. Other diseases evaluated by the doctor that are not suitable for the project.
- •Evaluated that the compliance for the intervention is not appropriate.
- •The blood glucose > 300mg/dl and unable to do vigorous exercise.
研究组 & 干预措施
Tai Chi Quan for Type 2 Diabetes
diabetic patients care education and Tai Chi Quan training, including 10-minute warm-up, 40-minute Tai Chi lesson, and 10-minute cool-down exercise in the training, twice a week for 12 weeks.
干预措施: Tai Chi Quan (Behavioral)
Control Group for Type 2 Diabetes
diabetic patients care education
结局指标
主要结局
Hemoglobin
时间窗: change from Baseline to 12 weeks
HbA1c
次要结局
- high and low density lipoprotein(change from Baseline to 12 weeks)
- quality of life(change from Baseline to 12 weeks)
- fasting blood glucose(change from Baseline to 12 weeks)
- estimated Glomerular Filtration Rate (eGFR)(change from Baseline to 12 weeks)
- low frequency (LF)(change from Baseline to 12 weeks)
- high frequency (HF)(change from Baseline to 12 weeks)
- heart rate variability(change from Baseline to 12 weeks)
- triglycerides(change from Baseline to 12 weeks)
- urine albumin/creatinine ratio (ACR)(change from Baseline to 12 weeks)
- creatinine(change from Baseline to 12 weeks)
- Glutamic-Pyruvic Transaminase (GPT)(change from Baseline to 12 weeks)