SLCTR/2014/005
Not yet recruiting
Phase 2
A randomized placebo controlled trial on the effect of insulin in reducing skeletal muscle reperfusion injury.
Professorial Surgical Unit0 sites24 target enrollmentTBD
ConditionsReperfusion injury
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Reperfusion injury
- Sponsor
- Professorial Surgical Unit
- Enrollment
- 24
- Status
- Not yet recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Patients undergoing a vascular surgical intervention requiring clamping of aortic / iliac or femoral blood vessels for more than 30 minutes duration and/or
- •2\. Patients with acute limb ischaemia, (Class ll Acute Limb Ischaemia, Society for Vascular Surgery) needing revascularization.
Exclusion Criteria
- •1\. Patients with any of the following.
- •a)Insulin\-treated diabetes mellitus
- •b)glucocorticoid treatment
- •c)systemic infection
- •d)congestive heart failure.
- •2\. Patients for whom amputation rather than revascularization is indicated.
- •3\. Patients below the age of 18 years
Outcomes
Primary Outcomes
Not specified
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