Effects of diet on the intestinal health of patients with liver fat
Not Applicable
- Conditions
- Fatty liver degeneration, not elsewhere classifiedK76.0
- Registration Number
- RBR-2rcph2
- Lead Sponsor
- Faculdade de Medicina de Universidade Federal de Juiz de Fora
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruitment completed
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
Age greater than 18 years; both genders; previous diagnosis of non-alcoholic steatohepatitis by means of liver biopsy.
Exclusion Criteria
Presence of chronic hepatitis B; chronic hepatitis C; autoimmune diseases of the liver; hemochromatosis; HIV-1 and 2-infected patients; patients with drug-induced; alcohol-induced liver disease (greater than 30 g / day in men or greater than 20 g / day in women); use of antibiotics in the two months prior to inclusion in the study.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Modulation of the fecal microbiota: result described in micro-gas density (x 108 g-1 cells), by fluorescent in situ hybridization technique <br><br>;Alteration of the bacterial overgrowth frequency in the small intestine: result expressed as a percentage and evaluated by respiratory test of exhaled hydrogen and methane.
- Secondary Outcome Measures
Name Time Method Changes in laboratory parameters: evaluation of hepatic transaminases, glycemic profile and lipid profile. Blood samples were collected and analyzed according to laboratory routine.;Change in anthropometric measurements and body composition: body weight, waist circumference, percentage of body fat and body mass index, by means of digital scale, tape measure and electric bioimpedance.