TCTR20210316015已完成1 期
Comparison of effectiveness between the oral administration and topical application of collagen on the reduction of skin wrinkles and roughness
/A0 个研究点目标入组 65 人开始时间: 2021年3月16日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 65
研究概览
简要总结
Oral administration and topical application of collagen, both groups were unable to reduce wrinkles and skin roughness, but it can help increase elasticity, moisture and reduce transepidermal water loss. In all parameters, it was found that the two groups showed no difference in effectiveness.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 36 Years 至 45 Years（—）
- 性别
- Female
入选标准
- •1. Not menopause
- •2. Sign in to the consent form to participate in the study
- •3. No history of allergy to fish food
- •4. Not a skin disease or Allergic rash at the area to be tested
- •5. There are no contraindications or restrictions on the intake of protein as indicated by the doctor.
- •6. Do not take other protein supplements or drugs that can affect the skin condition, such as roaccutane, tranxenamic acid, d-penicillamine. During the trial
- •7. Not received any treatment for the face including Dermabrasion, Iontophoresis, radiofrequency (RF) in a period of 1 month prior to participation.
- •8. Not received Botulinum toxin injection at the site to be tested within 8 months prior to participation.
- •9. Not received filler in the area to be tested within 1 year prior to participating
- •10. Not smoking
- •11. Lifestyle do not exposed to heat and sunlight for many hours without protection
- •12. Not pregnant or breastfeeding
排除标准
- •1. Want to leave research or have reasons to leave research
- •2. Pregnant during the study
- •3. Experiencing side effects or allergic reactions During the research
- •4. Forget to take collagen from 3 sachets per 4 weeks
- •5. More than 5 grams of skin product left per 4 weeks
- •6. Received any treatment for the face including injected with Botulinum toxin, Filler, laser during the research
- •7. There was a change in skin care and health behavior from the original during research
- •8. Appearance severe allergic rashes in the examination area
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