NCT00104312已完成不适用
Weakness From Inflammation: A Basis of Disability From Knee Osteoarthritis
National Institute on Aging (NIA)1 个研究点 分布在 1 个国家目标入组 88 人开始时间: 2001年4月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 88
- 试验地点
- 1
研究概览
简要总结
The purpose of this study is to understand the factors that lead to muscle weakness with arthritis and aging.
详细描述
Through this study, we hope to learn about the natural history of knee osteoarthritis and the disability that arises from it. We hope to better understand why people with knee osteoarthritis develop difficulty with mobility (e.g. walking, standing) in hopes of finding a cure.
This study requires 1 four-hour visit to Harbor Hospital. The visit involves a physical exam, a DEXA bone density scan, blood and urine testing, knee x-rays, strength testing and a surface electromyography (EMG). Samples of muscle, joint fluid and joint tissue will be collected during your planned surgery.
Participation in this study is entirely voluntary.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •50 years of age or older
- •Normal body weight (a Body Mass Index (BMI) of 30 or less)
- •Osteoarthritis of the knee (prior to knee surgery)
- •Planning to have knee surgery at a MedStar Hospital
排除标准
- •History of a stroke
- •History of muscle weakness or paralysis
- •History of Rheumatoid Arthritis or
- •Inflammatory Joint Disease
- •History of a Bleeding Disorder
- •History of Gout
- •Diabetes for which you take insulin
- •Polymyalgia rheumatica (total body muscle aching/stiffness)
研究者
研究点 (1)
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