Effect of 3 Years of Exercise in Patients With Atrial Fibrillation

Not Applicable

Completed

• Conditions: Atrial Fibrillation
• Interventions: Behavioral: Moderate exercise; Behavioral: Control; Behavioral: Interval exercise

• Registration Number: NCT01673139
• Lead Sponsor: Norwegian University of Science and Technology

Brief Summary

This is a substudy of "Generation 100". The investigators will follow the persons with atrial fibrillation to see if 3 years of interval or moderate exercise affects the burden of atrial fibrillation, symptoms, use of health services or echocardiographic findings.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2012-08-22
• Study First Submitted QC: 2012-08-22
• Study First Posted: 2012-08-27
• Study Start: 2012-09
• Primary Completion: 2018-08
• Study Completion: 2018-08
• Status Verified: 2018-11
• Last Update Submitted: 2018-11-16
• Last Update Posted: 2018-11-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 51

Inclusion Criteria

• Included in the "Generation 100 study"
• Atrial fibrillation diagnosis verified by ECG

Exclusion Criteria

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Moderate exercise	Moderate exercise	Moderate exercise
Control	Control	Control group
Interval exercise	Interval exercise	interval exercise

Primary Outcome Measures

Name	Time	Method
Change in burden of atrial fibrillation	At baseline and 3 years	Burden of atrial fibrillation; measured by Holter monitor and the patient.

Secondary Outcome Measures

Name	Time	Method
Quality of life	At baseline and 3 years	Measured with SF-36
Atrial extrasystoles	At baseline and 3 years	Measured with Holter monitor
Endothelial function	At baseline and 3 years	Diameter of brachial artery measured by ultrasound.
Number of hospitalisations with atrial fibrillation as main diagnosis	Total number during the 3 year intervention period
Maximal oxygen uptake	At baseline and 3 years
Function of left ventricle	At baseline and 3 years	Echocardiographic measures
Size of left ventricle	At baseline and 3 years	Echocardiographic measures
Total number of electrical cardioversions	During the 3 years of intervention	Number of electrical cardioversions because og atrial fibrillation
Change in burden of atrial fibrillation	Baseline and 1 year	Measured by Holter and the patient.
Symptom burden	At baseline and 3 years	Measured with Symptom and Severity Checklist.
Size of left atrium	At baseline and 3 years	Echocardiographic measures
Function of left atrium	At baseline and 3 years	Echocardiographic measures

Trial Locations

Locations (1)

Norwegian University of Science and Technology; 🇳🇴 Trondheim, Norway