Effect of transcutaneous auricular vagus nerve stimulation on postoperative cognitive function in patients during off-pump coronary artery bypass graft(OPCAG)
Not Applicable
- Conditions
- coronary heart disease
- Registration Number
- ChiCTR2400088701
- Lead Sponsor
- The Second Hospital of Hebei Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
(1) Age 45-80 years old<br>(2) ASA ?-?<br>(3) patients with off-pump coronary artery bypass graft(OPCAG)
Exclusion Criteria
(1) Patients with acute heart failure and acute myocardial infarction;<br>(2) Uncontrolled or poorly controlled hypertension;<br>(3) A history of renal or liver dysfunction;<br>(4) myasthenia gravis or mental disorders;<br>(5) The MMSE score is below 24 points<br>(6) A history of alcohol abuse or addiction to opioids or benzodiazepines;<br>(7) Expected airway difficulties.<br>(8) Previous ear trauma, lesions.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mini-mental State Examination,MMSE;CAM-ICU;
- Secondary Outcome Measures
Name Time Method White blood cell;C-reactive protein;TNF-a ;,IL-6 ;S-100ß ;(AChE);Dosage of opioids;