The Evaluation for Prognostic Factors After Catheter Ablation of Atrial Fibrillation: Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 3,100
- 试验地点
- 1
- 主要终点
- Clinical recurrence of atrial fibrillation (AF) after catheter ablation
研究概览
简要总结
- Purpose of the study
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To explore clinical recurrence associated clinical factors including age, sex, clinical, electrophysiological, anatomical, imaging, and serologic characteristics.
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To develop simulation model to predict clinical recurrence and the efficacy of catheter ablation 2. Scientific evidence of the study
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In atrial fibrillation patients, the maintenance of normal sinus rhythm showed significant reduction of mortality.
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drug therapy with anti-arrhythmic drug showed many complications and side effect, thus non-drug therapy such as catheter ablation is developed.
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catheter ablation has been performed for 10years world-wide, and showed superior treatment outcome compared with drug therapy.
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clinical outcome after catheter ablation is affected not only by age, sex and underlying disease, but also by electrophysiologic, imaging, serologic and electroanatomical remodeling of the heart. However, there are few studies concerning these multifactorial variables.
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Study population
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients who undergoing catheter ablation of atrial fibrillation due to symptomatic, drug refractory atrial fibrillation
排除标准
- •patients who do not agree with study inclusion
- •permanent AF refractory to electrical cardioversion
- •AF with valvular disease ≥ grade 2
- •patients with left atrial diameter greater than 60mm
- •patients with age less than 19
结局指标
主要结局
Clinical recurrence of atrial fibrillation (AF) after catheter ablation
时间窗: Participants will be followed for 5 year after catheter ablation
We defined recurrence of AF as any episode of AF or atrial tachycardia lasting longer than 30 sec. Patients were asked to attend scheduled outpatient follow-up appointments 2, 6, 12, 18, 24, 36, 48 and 60 months after catheter ablation.
次要结局
未报告次要终点