Tools for Health and Resilience Implemented After Violence Exposure (Project THRIVE)

Not Applicable

Completed

Brief Summary: Sexual assault victimization is a common and particularly harmful form of trauma that is associated with increased risk for high-risk drinking and other conditions of public health concern, such as PTSD. Given evidence that sexual assault survivors who have low social support or receive negative social reactions to sexual assault disclosure are more likely to experience PTSD and drinking problems, improving social support is a novel target for intervention. The proposed study will attempt to prevent the onset of high-risk drinking and PTSD in sexual assault survivors by developing and testing a web-based early intervention aimed at increasing contact with social supporters and mitigating the harm of negative social reactions; ultimately, results will contribute to advancing the field's understanding of the potential for social support to mitigate the harm of trauma.

Detailed Description: This study involves developing, modifying, and preliminarily testing an intervention to prevent high-risk drinking and PTSD in women who have experienced sexual assault (SA) in the past 10 weeks. In the pilot trial phase of this study, intervention feasibility will be tested in an open trial with N = 40 women with past-10-week SA histories, active drinking, and elevated distress. Participants will complete surveys at baseline, termination, and 3-month follow-up. Participants will be randomized to either the intervention (N = 20) or assessment-only control (N = 20). We hypothesize that (H1) most participants will respond positively on items assessing satisfaction with the intervention, (H2) participants will report above-average usability on a standardized measure, (H3) completion rates for daily activities will be similar to previous web-based interventions, (H4) participants will show significant learning as evidenced by increases in correct responses to knowledge questions from baseline to post, and (H5) participants in the intervention condition will evidence less high-risk drinking and PTSD at 3-month follow-up than participants in the assessment-only condition.

Recruitment & Eligibility

Inclusion Criteria

informed consent
self-identification as female
sexual assault, defined as endorsement of unwanted, attempted or completed sexual contact in the past 10 weeks
age > 18
English fluency
smartphone and internet access at least daily for 3 weeks and at least weekly for 3 months
consumption of >1 alcoholic drink in the past month
>1 episode of high-risk drinking in past 6 months, defined as either more than 3 drinks on a given day or more than 7 drinks in a given week
at least 3 symptom clusters endorsed on the PTSD Checklist.

Exclusion Criteria

Arm && Interventions

Group	Intervention	Description
Intervention	App-based intervention	The THRIVE app involves 3 weeks of daily activities. Day 1 involves identification of activities to add to a "self-care activity list" with guidance around selecting activities that increase social contact, reduce alcohol use, and reduce avoidance. They will also complete an active-learning exercise about cognitive distortions and create a "stuck point to-do list" consisting of their cognitive distortions. In subsequent days, participants will be prompted to complete activities from both lists. They will also have access optional activities on topics such as asking for help, preventing isolation, deciding whether to disclose an assault, coping with negative reactions to disclosure, and thinking in helpful ways about social support. They will be prompted to complete brief daily surveys in the app, which will populate a symptom tracker. Participants in will have brief weekly phone contact with a coach to monitor safety and troubleshoot issues with app use.

Primary Outcome Measures

Name	Time	Method
Posttraumatic Stress Symptom Severity Score at Baseline and 3 Weeks	Baseline, post-intervention (3 weeks after baseline)	Sum scores on the Posttraumatic Stress Disorder Checklist for the Diagnostic and Statistical Manual of Mental Disorders-5 (PCL-5), which assesses posttraumatic stress symptom severity. Range: 0-80; higher scores indicate worse outcome.
Posttraumatic Stress Symptom Severity Score at Baseline and 3 Months	Baseline, 3 month follow-up	Sum scores on the Posttraumatic Stress Disorder Checklist for the Diagnostic and Statistical Manual of Mental Disorders-5 (PCL-5), which assesses posttraumatic stress symptom severity. Range: 0-80; higher scores indicate worse outcome.
Problem Drinking Scores at Baseline and 3 Months	Baseline, 3 month follow-up	Sum scores on Rutgers Alcohol Problem Index- Short Form (RAPI-S), which assesses alcohol use consequences. Range: 0-64; higher scores indicate worse outcome.
Problem Drinking Scores at Baseline and 3 Weeks	Baseline, post-intervention (3 weeks after baseline)	Sum scores on Rutgers Alcohol Problem Index- Short Form (RAPI-S), which assesses alcohol use consequences. Range: 0-64; higher scores indicate worse outcome.

Secondary Outcome Measures

Name	Time	Method
Alcohol Consumption (Frequency)	Baseline, post-intervention (3 weeks after baseline), 3 month follow-up	Number of drinking days per week reported on the Daily Drinking Questionnaire
Alcohol Consumption (Hours)	Baseline, post-intervention (3 weeks after baseline), 3 month follow-up	Hours spent drinking per week reported on the Daily Drinking Questionnaire
Anxiety	Baseline, post-intervention (3 weeks after baseline), 3 month follow-up	Sum scores on Generalized Anxiety Disorder-7 (GAD-7), which assesses symptoms of anxiety. Range: 0-21; higher scores indicate worse outcome.
Coping Self-efficacy	Baseline, post-intervention (3 weeks after baseline), 3 month follow-up	Mean scores on the Trauma Coping Self-Efficacy Scale (CSE-T), which assesses one's perceived ability to manage the demands of recovering from a potentially-traumatic event. Range: 1 to 7; higher scores indicate better outcome.
Depression	Baseline, post-intervention (3 weeks after baseline), 3 month follow-up	Sum scores on the Patient Health Questionnaire-8 (PHQ-8), which assesses symptoms of depression. Range: 0-24; higher scores indicate worse outcome.
Alcohol Consumption (Quantity)	Baseline, post-intervention (3 weeks after baseline), 3 month follow-up	Number of drinks per week reported on the Daily Drinking Questionnaire

Locations (1): University of Washington School of Medicine
🇺🇸
Seattle, Washington, United States