Physical activity and health: the effect of GoldFit YMCA participation on brain, breathing and blood pressure regulation in older adult humans - a longitudinal study.

Not Applicable

• Conditions: Cardiovascular - Hypertension; Cardiovascular disease; Cardiovascular - Coronary heart disease; Cardiovascular - Other cardiovascular diseases

• Registration Number: ACTRN12622000036718
• Lead Sponsor: niversity of Auckland

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-01-17
• Last Update Posted: 24 January 2022

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Aged >60 years old
- Men and women
- Free of chronic cardiovascular, respiratory, metabolic, or neurological disease
- Not currently engaging in regular exercise and have not been in a regular exercise routine for >12 months, and who are newly enrolled or intending to enroll to begin exercise training in the YMCA GoldFit exercise training programme, aged >60 years old

Exclusion Criteria

•BMI <18 kg/m2
•Current smoker
•Current users of recreational drugs
•Current abusers of alcohol
•Recent (<12 month) history of hospital admission
•Significant arrhythmias (e.g., atrial fibrillation, previous VT / significant ventricular ectopy)
•Hemodynamically significant valvular heart disease (e.g., stenosis, mechanical valve replacement)
•Severe left ventricular systolic dysfunction
•Recent acute coronary syndrome (<12 months) (e.g., MI, angioplasty, unstable angina)
•Previous coronary artery bypass surgery
•Secondary causes of hypertension (e.g., phaeochromocytoma)
•Recent stroke/TIA (<12 months)
•Inability to fully or appropriately provide consent (e.g., language issue, reading capability)
•Underlying medical conditions, which in the opinion of the Investigator place the participant at unacceptably high risk for participating in the study.
Chronic and systemic illness including:
•Severe respiratory disease (e.g., chronic obstructive pulmonary disease);
•Severe, uncontrolled type II diabetes;
•Current treatment for cancer or complete remission <5 years
•Connective tissue or inflammatory disease
•Neurological / psychiatric disease (e.g., peripheral neuropathy, dementia, Parkinson’s, epilepsy)
•Infection or pyrexial illness
•Uncontrolled thyroid disorders
•Renal impairment (e.g., eGFR <60)
•Liver disease

Study & Design

• Study Type: Interventional
• Study Design: Not specified