Risk of spontaneous bacterial peritonitis after colonoscopy in hydrop decompensated liver cirrhosis

Recruiting

• Conditions: K74.6; K65.0; Other and unspecified cirrhosis of liver; Acute peritonitis

• Registration Number: DRKS00028583
• Lead Sponsor: Klinikum der Johann Wolfgang Goethe-Universität Frankfurt am Main

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-03-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 76

Inclusion Criteria

Indication to perform colonoscopy in the presence of concomitant liver cirrhosis with ascites
- Age at least 18

Exclusion Criteria

- Contraindication to ascites puncture (e.g., uncontrolled coagulopathy).
- Presence of SBP prior to performing colonoscopy
- Pregnancy and lactation

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Evidence of spontaneous bacterial peritonitis or bacterascites within 72 h of performing colonoscopy. <br><br>Diagnostic criteria of SBP: neutrophil count in ascites >/= 250/µl with or without positive ascites culture.<br><br>Diagnostic Criteria Bacterascites: <br>Positive ascites culture + neutrophil count <250/µl

Secondary Outcome Measures

Name	Time	Method
Total ascitic fluid protein concentration, postinterventional development of renal failure, initiation/adjustment of antibiotic therapy, occurrence of sepsis, admission to intensive care unit, survival time.