AN OPEN CLINICAL TRIAL ON ESSENTIAL HYPERTENSION-KURUTHIAZHAL MANAGED WITH KURUTHIAZHAL KUDINEER (KK) A SIDDHA HERBAL CONCOCTION
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Good – reduction of BP down to 130/80 mmHg and below.
研究概览
简要总结
Hypertension is the most common cardiovascular diseases and is a major public health issue in developed as well as developing countries. Although it is common and readily detectable, it can often lead to lethal complication, if left treated.Primary hypertension is the most common type of hypertension, accounting 95% of hypertensive patients. It has no identifiable cause. It is the primary cause of stroke, coronary artery diseases and sudden cardiac death. In Worldwide, the majority of diagnosed hypertensive patients are inadequately controlled.
In National Institute of Siddha hospital ,the number of Kuruthiazhal (hypertension) patients are gradually increasing. Many more Siddha formulations are mentioned in Siddha text for the treatment of Kuruthiazhal. According to the Siddha literature, selected drug is indicated for kuruthiazhal. Here I have chosen Kuruthiazhal kudineer being used by many traditional practitioners and found to be effective in management of hypertension
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
- 盲法
- Open Label
入排标准
- 年龄范围
- 25.00 Year(s) 至 60.00 Year(s)（—）
入选标准
- •1 Age : 25 to 60 years 2 Patients who are reported with complaints and / or findings of primary hypertension at NIS OPD/IPD with or without Anti hypertensive medication 3 Gender: All genders SYSTOLIC PRESSURE: 140-179 mmHg [ Grade I & II – Stage I ] DIASTOLIC PRESSURE: 90-109 mmHg [ Grade I & II – Stage I ].
排除标准
- •1 Secondary hypertension due to following causes Chronic kidney disease MRD (Medical Renal Disease) as found out by USG Symptom of orthostatic hypertension suggestive of Pheochromocytoma 2 Hypertension associated Cerebro vascular disease Cardio vascular disease Ischemic heart disease Obstructive sleep apnea Thyroid dysfunction Uncontrolled diabetes 3 Vulnerable group-Pregnancy induced hypertension.
结局指标
主要结局
Good – reduction of BP down to 130/80 mmHg and below.
时间窗: 1 year
Moderate - reduction of BP down to 140/90 mmHg and below.
时间窗: 1 year
Poor – Partial / No reduction in BP but missing the target.
时间窗: 1 year
次要结局
- Good – reduction of BP down to 130/80 mmHg and below.(Moderate - reduction of BP down to 140/90 mmHg and below.)