A pragmatic randomised controlled trial to test the efficacy of nortriptyline plus nicotine replacement therapy (NRT) versus a placebo plus NRT in helping smokers to stop and testing the role of noradrenergic and dopaminergic genetic variants in smoking cessatio

Completed

• Conditions: Smoking cessation; Mental and Behavioural Disorders

• Registration Number: ISRCTN57852484
• Lead Sponsor: niversity of Birmingham (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2005-07-25
• Last Update Posted: 2015-01-13

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 900

Inclusion Criteria

1. Smoked at least 10 cigarettes per day on average over the past year.
2. Want to quit
3. Prepared to use NRT and the trial drug
4. Using an NHS stop smoking service

Exclusion Criteria

1. Pregnant or breast feeding or planning to do so in the next 3 months
2. Not clinically suitable to use NRT according to data sheet
3. Not clinically suitable to use nortriptyline according to data sheet

Study & Design

• Study Type: Interventional
• Study Design: Not specified