The effects of Dexmedetomidine and Midazolam on hemodynamic responses after tracheal intubation in elderly patients under Cataract surgery with general anesthesia in comparison to control group

Phase 2

Conditions: Condition 1: Cataract surgery. Condition 2: Tracheal intubation.
Cataract in diseases classified elsewhere
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
Y84.8

Registration Number: IRCT20200510047389N2

Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 210

Inclusion Criteria

Elderly patients over 65 years old candidate for cataract surgery with general anesthesia
ASA2-3
No allergy to any of the study medications

Exclusion Criteria

Hemodynamic changes over 30% that needed intervention
Patient who refusing
Severe drug complications
History of using opioid and alcohol
Changing the method of anesthesia
Severe chronic disease

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Systolic Blood pressure. Timepoint: Before the anesthesia, 1, 3, 5, 10 during anesthesia, entering the recovery and discharge time. Method of measurement: Blood pressure monitoring device.;Diastolic blood pressure. Timepoint: Before the anesthesia, 1, 3, 5, 10 during anesthesia, entering the recovery and discharge time. Method of measurement: Blood pressure monitoring device.;Mean arterial Blood pressure. Timepoint: Before the anesthesia, 1, 3, 5, 10 during anesthesia, entering the recovery and discharge time. Method of measurement: Blood pressure monitoring device.;Heart rate. Timepoint: Before the anesthesia, 1, 3, 5, 10 during anesthesia, entering the recovery and discharge time. Method of measurement: Monitoring device.;Arterial oxygen saturation percentage. Timepoint: Before the anesthesia, 1, 3, 5, 10 during anesthesia, entering the recovery and discharge time. Method of measurement: Pulse oximetry.

Secondary Outcome Measures

Name	Time	Method
Surgery complictions. Timepoint: After the surgery in recovery. Method of measurement: Physical examination and observation by physician.;Recovery time. Timepoint: After the surgery. Method of measurement: Minute.