Simulated Walking With Multiplexing Prism for Field Expansion in Monocular Vision

Not Applicable

Terminated

• Conditions: Blind Right Eye; Blind Left Eye; One Eye Blindness
• Interventions: Device: Multiplexing Prism

• Registration Number: NCT06024668
• Lead Sponsor: Massachusetts Eye and Ear Infirmary

Brief Summary

The investigators are developing an assistive device, known as multiplexing prism that expands the field of view for individuals with acquired monocular vision (loss of an eye). The investigators will test the efficacy of the prism in improving the detection of colliding pedestrians during a simulated walking task.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-08-29
• Study First Submitted QC: 2023-08-29
• Study First Posted: 2023-09-06
• Study Start: 2024-08-04
• Primary Completion: 2024-10-28
• Study Completion: 2024-10-28
• Status Verified: 2025-03
• Last Update Submitted: 2025-03-31
• Last Update Posted: 2025-04-03

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 1

Inclusion Criteria

• No medical health issues such as seizures, motor movements problem
• Loss of vision in one eye (less than 20/200) for >1 year
• Visual acuity of the seeing eye: Better than 20/32 visual acuity with correction
• No visual field defect in the seeing eye (nasal field of at least >45degree)

Exclusion Criteria

• Patients with any physical or mental disabilities, including cognitive dysfunction, balance problems, or other deficits that could impair their ability to respond to the stimuli presented in this study will be excluded
• Any person with a history (such as pacemaker use or photosensitive epilepsy)
• Any person with motor movements problem (e.g., unable to use extremities)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Detection of colliding pedestrian	Multiplexing Prism	Participants will perform a simulated walking task in which surrounding pedestrians will walk towards and make a collision. Participants will respond by pressing buttons to indicate the direction of the colliding pedestrians. Participants will perform the task with and without the multiplexing prism in random orders.

Primary Outcome Measures

Name	Time	Method
Mean response time to detect colliding pedestrian	Approximately 3 sessions, up to 3 hours for each session, any time within 4 month period	The investigators will compare the mean response time to detect colliding pedestrians coming from the nasal (same side as the blind eye) and temporal (same side as the seeing eye) visual field with and without multiplexing prism. The comparison will be made between these four: Nasal without prism, Temporal without prism, Nasal with prism, and Temporal with prism.

Secondary Outcome Measures

Name	Time	Method
Pedestrian Detection Rate	Approximately 3 sessions, up to 3 hours for each session, any time within 4 month period	The investigators will measure the rate of correct detection rate of colliding pedestrians in the nasal (same side as the blind eye) and temporal (same side as the seeing eye) with and without multiplexing prism. Comparisons will be made for these: nasal without prism, temporal without prism, nasal with prism,and temporal with prism.

Trial Locations

Locations (1)

Schepens Eye Research Institute; 🇺🇸 Boston, Massachusetts, United States