Transcranial direct current stimulation for the treatment of anorexia nervosa: A pilot study
- Conditions
- Anorexia nervosaMental Health - Eating disorders
- Registration Number
- ACTRN12618001966280
- Lead Sponsor
- Swinburne University of Technology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Stopped early
- Sex
- Female
- Target Recruitment
- 8
Inclusion criteria include being female, right-handed, English speaking, over 18 year of age and right-handed with a current diagnosis of anorexia nervosa according to DSM-5 criteria. All participants will be required to have ongoing medical support during the course of the intervention. All participants will also be required to be medically stable and stable on any medications for one month prior to inclusion in the study.
Participants will not be included in the study if they have a comorbid psychotic condition, substance/alcohol abuse/dependence, any history of neurological illness, any history of head injury, or any significant ocular pathology. Participants must not be undergoing any brain stimulation intervention currently, or in the past year. As participants will be required to undergo an MRI a number of further exclusions for safety purposes will be required including that the participant is not pregnant or breastfeeding, they do not have any irremovable metal (ferromagnetic metals) in their body and do not suffer from claustrophobia.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Eating Disorder Examination Questionnaire (full version and short-form)<br>[ Post-tDCS];Composite outcome: Anorexia nervosa symptom scales designed for the study (Likert scale ratings including urge to eat, urge to exercise, urge to restrict, feeling of fatness, feeling of fullness, mood and anxiety)[ post-tDCS];Square wave jerk rate (atypical eye movement present in individuals with anorexia nervosa), This will be assessed with the EyeLink1000 Plus remote-view eyetracking system with a sampling rate of 1000Hz.[ post-tDCS]
- Secondary Outcome Measures
Name Time Method Eating Disorder Examination Questionnaire (full version and short-form)[ 4- and 12-weeks post-tDCS];Composite outcome: Anorexia nervosa symptom scales designed for the study (Likert scale ratings including urge to eat, urge to exercise, urge to restrict, feeling of fatness, feeling of fullness, mood and anxiety)[ 4- and 12-weeks post-tDCS];Square wave jerk rate (atypical eye movement present in individuals with anorexia nervosa). This will be assessed with the EyeLink1000 Plus remote-view eyetracking system with a sampling rate of 1000Hz.[ 4- and 12-weeks post-tDCS];Body mass index (Tanita body composition monitor, measuring tape for height) (body weight divided by height in metres squared)[ post-tDCS, 4- and 12-weeks post-tDCS]