eurostimulation of the motor area and its effects on anxiety, depression and inflammation in patients with rheumatoid arthritis

Not Applicable

• Conditions: Anxiety; Depression; C05.550.114.154; C23.888.592.612.274

• Registration Number: RBR-2v2k9gg
• Lead Sponsor: niversidade Federal do Amazonas

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-07-08
• Study Completion: 2023-04-29
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Patients with chronic pain manifested for a minimum period of 12 weeks; in clinical treatment with synthetic DMARDs; who present pain in intensity greater or equal 7 by the visual analogical pain scale (EVA-Dor); Who present anxiety symptoms according to the Beck scale (psychological assessment instrument, BAI, Beck Anxiety Inventory); who present symptoms of depression according to the Beck psychological assessment instrument, BDI, Beck Depression Inventory

Exclusion Criteria

Patients who have other autoimmune diseases not related to AR; Who are being treated with biological DMARDs; pregnant women; who have a clinical diagnosis of major depressive disorder (greater than 30 in the evaluation score according to Beck Depression Inventory, BDI); with clinical diagnosis of generalized anxiety disorder (GAD), (greater than 31 in the evaluation score according to Beck Anxiety Inventory, BAI); patients with a history of skin diseases; who use high doses of opioids; with a history of illicit drug use/abuse; with metal implants in the cranial or facial region; that use pacemakers; with a history of seizures or epilepsy; with neurological, cognitive and motor deficits; patients who underwent craniotomy; patients with cancer diagnosis; decompensated disease (ischemic heart disease, kidney and/or liver diseases)

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The effect of transcranial direct current stimulation (tDCS) on the motor area on symptoms of anxiety and depression in patients with chronic pain diagnosed with Rheumatoid Arthritis (RA)