Effects of transcranial direct current stimulation for improving attention after traumatic brain injury

Not Applicable

Completed

• Conditions: traumatic brain injury; Injuries and Accidents - Other injuries and accidents; Neurological - Other neurological disorders

• Registration Number: ACTRN12619001523190
• Lead Sponsor: SW

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2018-10-11
• Study Start: 2019-11-04
• Last Update Posted: 11 November 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Definite moderate to severe traumatic brain injury according to the Mayo classification criteria (Malec, Brown, Leibson et al, 2007), i.e.
a period of post-traumatic amnesia (PTA) of 24 hours or greater and/or
loss of consciousness greater than 30 minutes and/or
evidence of intracerebral brain pathology on neuroimaging.
- Aged between 18 – 70 years,
- At least 12 months post-injury,
- Discharged from hospital and living in the community,
- Functional English reading and writing ability.

Exclusion Criteria

-Uncorrected hearing or vision loss.
-Current diagnosed drug and/or alcohol addiction
- Active psychosis
-Psychiatric condition (other than mild to moderate anxiety or depression).
-Dementia or other neurodegenerative disease
-Aphasia, agnosia, or profound amnesia
- Insertion of a metal shunt.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Accuracy (d prime) of performance on 1-Back working memory task[During active/sham tDCS];Reaction time and reaction time SD (variability) on 1-Back working memory task[During sham/active tDCS];Task activated arousal (difference in skin conductance levels between rest (eyes closed, eyes open, eyes closed (see procedure) and during 1-back task.<br><br>Skin conductance was recorded from silver-silver chloride (Ag/AgCl) bipolar electrodes filled with electrode paste of 0.05 M NaCl in an inert ointment base, placed on the distal volar surface of digits II and III of the non-dominant hand, with a PowerLab 8/30 Data Acquisition System (AD Instruments, Castle Hill, Australia). SCL was calibrated for each participant at the start of their recording session to detect activity in the range of 0–40 µS and digitized at a sampling rate of 1000 Hz. [During active/sham tDCS]