Characteristics and Prehospital Triage of Anterior Large Vessel Occlusion Stroke Based on EEG
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 1,194
- 试验地点
- 1
- 主要终点
- Saline electrode EEG characteristics: area under the ROC curve for theta/alpha ratio;
研究概览
简要总结
This study is designed to evaluate the accuracy of saline electrode EEG in the prehospital diagnosis of LVO-a stroke.
详细描述
This is a multicenter, prospective, observational study,which will screen a total of 1194 patients in the participating centers during the period of June 1, 2024-December 31, 2025, and record single scalp EEG signals with eyes open at rest in the lying position of the patients using a non-invasive EEG acquisition device, and collect clinical data.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Phase I.1.Acute ischemic stroke caused by occlusion of the anterior circulation (intracranial origin of the internal carotid artery or proximal middle cerebral artery (M1/M2)) confirmed by CTA, MRA or DSA (diagnosis in accordance with the "Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2023")；
- •Patient age ≥18 years；3: Last normal time to EEG acquisition time ≤ 72 hours；4: Signed informed consent.
- •Phase II-III
- •Diagnosed by a healthcare professional as a suspected acute stroke patient or a known acute stroke patient
- •Patient age ≥18 years
- •Last normal time to EEG acquisition time ≤ 24 hours
- •Signed informed consent
排除标准
- •Wounds in the area of electrode cap placement or active infection in the scalp;
- •Patients who do not cooperate with the EEG examination.
结局指标
主要结局
Saline electrode EEG characteristics: area under the ROC curve for theta/alpha ratio;
时间窗: 24 hours
Accuracy of theta/alpha ratio of electroencephalographic features for the diagnosis of large vessel occlusion Accuracy of theta/alpha ratio of electroencephalographic features for the diagnosis of anterior large vessel occlusion stroke
次要结局
- Other EEG features including relative δ, θ, α power, δ/α ratio, δ+θ/α+β ratio, pdBSI, and WPLI diagnostic accuracy for LVO-a;(24 hours)
- Development of one or more new algorithms for optimal diagnosis of LVO-a based on EEG data(24 hours)
- Logic and technical feasibility of saline electrode EEG in ambulance for suspected stroke patients by paramedics;(24 hours)
研究者
Junwei Hao, MD
Characteristics and prehospital triage of anterior large vessel occlusion stroke based on EEG
Xuanwu Hospital, Beijing