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Screening Volunteers for Clinical Trials

Recruiting
Conditions
Screening
Registration Number
NCT01375530
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Brief Summary

Background:

- The National Institute of Allergy and Infectious Diseases (NIAID) at the National Institutes of Health needs healthy volunteers for vaccine clinical trials. This is a screening study that is used to identify healthy volunteers who may be eligible to participate in other clinical trials at the Vaccine Research Center that evaluate investigational vaccines, monoclonal antibodies, and injection devices. The VRC conducts studies that will allow researchers to better understand the immune system and how vaccines and monoclonal antibodies work.

Objectives:

- To screen healthy volunteers for clinical trials at the NIAID VRC.

Eligibility:

- Healthy people between 18 and 60 years of age. They must be available to take part in clinical trials and be able to provide blood for research studies.

Design:

* Screening for healthy volunteers to participate in clinical trials is an ongoing process.

* Volunteers will be asked about their medical history, including sexual activity and drug use, and a detailed physical exam will be performed.

* Blood and urine samples may be collected, and possibly other tests as needed to evaluate the volunteer's health status.

* Volunteers will not receive any investigational product in this screening protocol.

Detailed Description

The purpose of this study is to recruit and screen potential study subjects, mostly healthy volunteers, to determine if they are eligible for clinical trials of investigational products. This screening study also aims to characterize and analyze demographic information as well as laboratory and other medical findings in terms of how they may affect the eligibility of subjects for specific early phase clinical trials. All work will be conducted by the VRC Clinic of the National Institutes of Health or other IRB-approved sites that are collaborating with NIAID/VRC. Educational and recruitment materials on the investigational products and protocols will be

reviewed with and provided to subjects during participation in the screening protocol.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
4000
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To screen subjects for their eligibility to participate in clinical trials.Ongoing

Duration of subject participation is variable, and may last from a few weeks to several months for each subject.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (4)

Emory University

🇺🇸

Atlanta, Georgia, United States

University of Pennsylvania-UPenn

🇺🇸

Philadelphia, Pennsylvania, United States

Univ of MD School of Medicine Center for Vaccine Development & Global Health

🇺🇸

Baltimore, Maryland, United States

National Institutes of Health Clinical Center

🇺🇸

Bethesda, Maryland, United States

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