Coronary Anatomy Study and Times Since the Onset of Acute Myocardial Infarction Symptoms in Women Until the Opening of the Artery (TAPAC Study)

Completed

• Conditions: Myocardial Infarction
• Interventions: Other: Non intervention

• Registration Number: NCT03152240
• Lead Sponsor: Hospital Universitari Vall d'Hebron Research Institute

Brief Summary

TAPAC study is an an investigator-driven, observational, prospective,cohort aimed at evaluating differences between men and women in patients undergoing primary angioplasty : hospital medical care, successful markers myocardial reperfusion and the anatomical substrate by describing the underlying coronary anatomy will be compared.

Detailed Description

TAPAC study is an an investigator-driven, observational, prospective,cohort aimed at evaluating differences between men and women in patients undergoing primary angioplasty : hospital medical care, successful markers myocardial reperfusion and the anatomical substrate by describing the underlying coronary anatomy will be compared.

Study Timeline

• Study First Submitted: 2017-05-04
• Study First Submitted QC: 2017-05-11
• Study First Posted: 2017-05-12
• Study Start: 2017-11-01
• Status Verified: 2019-02
• Primary Completion: 2019-02-26
• Study Completion: 2019-02-26
• Last Update Submitted: 2019-02-26
• Last Update Posted: 2019-02-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 800

Inclusion Criteria

Patients with:

• Aged 18 years or over.
• AMI (Acute Mycardial Infarction ) with ST segment elevation and indication of primary angioplasty in whom at least one diagnostic procedure with coronary angiography is performed.

Exclusion Criteria

Patients with:

• Life expectancy of less than one year.
• Previous AMI.
• Previous coronary revascularization.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Men patients	Non intervention	Men patients
Women patients	Non intervention	Women patients

Primary Outcome Measures

Name	Time	Method
Time from onset of chest pain to first medical care	24 hours	Time from onset of chest pain to first medical care
Door-to-balloon time in patients	90 minutes	Door-to-balloon time in patients
Door-to-needle time in patients	90 minutes	Door-to-balloon time in patients
Time from onset of chest pain to arrival Cath Lab	24 hours	Time from onset of chest pain to arrival Cath Lab
Underlying coronary anatomy assessment	24 hours	Degree of distal embolization
Time from onset of chest pain to artery opening	24 hours	Time from onset of chest pain to artery opening
Markers successful myocardial reperfusion by angiography	First 90 min after reperfusion.	Final TIMI blush grade

Secondary Outcome Measures

Name	Time	Method
Major adverse cardiac events (MACE)	Hospital discharge and expected average of 1 week, one year follow-up	MACE rate during hospitalization, defined as death, non-fatal myocardial rupture, or appearance or worsening of heart failure during the hospitalization period and after 1 year of follow-up

Trial Locations

Locations (1)

Hospital Universitari Vall d'Hebron; 🇪🇸 Barcelona, Spain