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Clinical Trials/NCT02466776
NCT02466776
Completed
Not Applicable

Comparison of Staples Versus Subcuticular Suture in Class III Obese Women Undergoing Cesarean Delivery

MemorialCare Health System4 sites in 1 country238 target enrollmentJune 2015

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Obesity, Severe
Sponsor
MemorialCare Health System
Enrollment
238
Locations
4
Primary Endpoint
Composite Wound Complication at Hospital Discharge and 2 Weeks Postpartum
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The purpose of this study is to determine the optimal skin closure technique (staples versus subcuticular suture) at the time of cesarean delivery in Class III obese women with body mass index (BMI) of >/= 40kg/m2.

Detailed Description

A. To assess the rate of wound complications with staples versus subcuticular suture closure in women with a BMI of ≥ 40 kg/m2 undergoing cesarean delivery (CD). B. No difference was observed in wound complication rates between staples and subcuticular suture skin closure in women with a BMI ≥ 40 kg/m2 undergoing cesarean delivery (CD). C. At this time, optimal skin closure method in obese women with BMI ≥ 40 kg/m2 undergoing cesarean delivery remains unknown. More work is needed in this area to help reduce the complication rate in this very high-risk population.

Registry
clinicaltrials.gov
Start Date
June 2015
End Date
November 2015
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Jennifer McNulty, MD

Maternal Fetal Medicine Specialist

MemorialCare Health System

Eligibility Criteria

Inclusion Criteria

  • Women \> 18 years old undergoing cesarean delivery (CD)
  • BMI of \>/= 40 kg/m2 as determined by height and weight reported during their admission
  • Live gestation 23 weeks or greater
  • Women who are able to follow-up 7-14 days after hospital discharge for a visual wound check.

Exclusion Criteria

  • Active lupus flare
  • Current treatment for cancer or h/o radiation to the abdomen/pelvis
  • Hypersensitivity to steri-strips

Outcomes

Primary Outcomes

Composite Wound Complication at Hospital Discharge and 2 Weeks Postpartum

Time Frame: At hospital discharge, at 2 weeks postpartum and at 6 weeks postpartum

Rate of wound complications defined as composite wound complication, which includes infection requiring antibiotics, hematoma, seroma, separation or disruption, and/or readmission to the hospital for wound concerns.

Secondary Outcomes

  • Number of Participants With Blood Transfusion(At time of surgery and hospitalization)
  • Number of Participants Receiving Postpartum Prophylactic Anticoagulation(During hospitalization)
  • Patient Pain Score (From 1 to 10)(Within 2 weeks postpartum)
  • Number of Participants With 5 Minute Apgar Score <7(At time of delivery)
  • Total Length of Hospital Stay(At time of surgery and hospitalization)
  • Number of Participants According to Skin Incision(At time of surgery and hospitalization)
  • Operating Surgeon Level(At time of surgery)
  • Surgical Assistant Level(At time of surgery)
  • Change in Hemoglobin (Pre-delivery and Post-delivery)(At time of surgery (pre-delivery) and post-delivery)
  • Patient Satisfaction With Wound Healing and Appearance(At time of hospital discharge and at 2 weeks postpartum)
  • Total Operative Time(At time of surgery and hospitalization)
  • Total Blood Loss(At time of surgery)
  • Neonatal Birthweight(At time of delivery)

Study Sites (4)

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