Crossover in vivo study: investigation of the redox status of study participants before and after ingestion of vitamin C in blood.
Not Applicable
- Conditions
- Healthy volunteers
- Registration Number
- DRKS00028934
- Lead Sponsor
- Charité-Universitätsmedizin Berlin, Dermatologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 28
Inclusion Criteria
Inclusion Criteria
The studies will be conducted on study participants who
- are healthy
- are between 20 and 60 years old
- Are informed about the aims of the study and the nature of the investigations
- your informed consent to participate, have given in writing.
Exclusion Criteria
With exception of
- Persons with allergies or intolerance reactions to food
- Children
- Pregnant and nursing mothers
- Individuals who have given their informed consent have not given in writing
- Persons who are not self-responsible can make decisions
- Charité students in the exam semester
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The in vivo study aims to show that increasing the dose of vitamin C in physiological concentrations leads to antioxidant protection that can be quantitatively/qualitatively demonstrated in the blood. However, if the critical vitamin C concentration is exceeded, there can be an increased formation of free radicals (prooxidative effect) in the blood.
- Secondary Outcome Measures
Name Time Method Finally, a method for determining the redox status in blood after UV stress induction for electron spin resonance (ESR) spectroscopy is to be developed, which can determine the redox status in blood and assess the supply of antioxidants. Finally, a method for determining the redox status in blood after UV stress induction for electron spin resonance (ESR) spectroscopy is to be developed, which can determine the redox status in blood and assess the supply of antioxidants.