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Comparison of two dialysis modes: nocturnal haemodialysis (NHD) and haemodiafiltration (HDF) in haemodialysis patients.

Not Applicable
Completed
Conditions
haemodialysis
Renal and Urogenital - Kidney disease
Registration Number
ACTRN12615000517572
Lead Sponsor
Prof Peter Kerr
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
12
Inclusion Criteria

existing nocturnal haemodialysis patients
have been stable on NHD for at least 3 months
permanent vascular access

Exclusion Criteria

planned transplant
not able to provide consent
not able to adhere to protocol

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
serum biochemical parameters of dialysis adequacy (urea, phosphate, B2microglobulin, retinol binding protein, fetuin, FGF-23, alpha-1 microglobulin) as a composite outcome[Biochemical assessment at baseline and at the end of 2 weeks of each treatment option.];dialysate based assessment of removal of urea and phosphate[baseline and at the end of each 2-week treatment phase.]
Secondary Outcome Measures
NameTimeMethod
cardiovascular stability - as assessed by blood pressure during dialysis.[during the last dialysis session of each 2-week treatment phase.]
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