Voice Analysis for Monitoring Patients With Heart Failure
- Conditions
- Heart Failure
- Registration Number
- NCT06566911
- Lead Sponsor
- Noah Labs
- Brief Summary
This observational study involves ADHF patients at two sites in the United States and Germany. After informed consent and screening assessments, participants will perform daily voice recordings during their hospital stay, from admission until discharge. Alongside voice data, additional clinical information such as left ventricular ejection fraction, NTpro-BNP levels, and ECG-data will be collected for comprehensive analysis. The study's goal is to identify voice-based indicators of heart failure progression, with the potential to enhance remote monitoring and self-management strategies for heart failure patients.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 70
- Clinically diagnosed with Acutely Decompensated Heart Failure.
- At least 18 years of age.
Exclusion criteria:
- Disabling mental diseases (e.g., Alzheimer's disease)
- Clinically diagnosed chronic obstructive pulmonary disease (COPD)
- Treatment in ICU or IMU
- Dialysis treatment
- Previous operations on organs involved in generation of voice (vocal tract, vocal folds, etc.)
- Neurodegenerative diseases
- Pregnancy
- Inability to provide consent
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in vocal characteristics from admission to discharge and their correlation with heart failure severity markers. Hospital stay The primary endpoint is the change in vocal characteristics from admission to discharge, and its correlation with clinical markers of heart failure severity, such as weight change from admission to discharge, NTpro-BNP levels, ECG-parameters, and left ventricular ejection fraction (LVEF).
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
Mayo Clinic
🇺🇸Rochester, Minnesota, United States
Deutsches Herzzentrum der Charité
🇩🇪Berlin, Germany