ketamine combination with propofol, dexmedetomidine or fentanyl for sedation in dressing in burn patients
- Conditions
- Health Condition 1: T31- Burns classified according to extent of body surface involvedHealth Condition 2: O- Medical and Surgical
- Registration Number
- CTRI/2022/08/044869
- Lead Sponsor
- AIIMS
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
All ASA 1-2 patients aged >18 years with burn injury having superficial to partial thickness burns scheduled for burn dressing.
a)Patients with any serious co-morbidities like cardiovascular disease, cerebrovascular disease , intracranial hypertension and respiratory tract infection
b)Sinus bradycardia
c)Deep burns or >50% burns
d)History of substance abuse or dependence like alcohol
e)Patients requiring mechanical ventilation
f)Patients requiring vasopressor support
g)Patients in the initial resuscitation phase
h)Difficult airway
i)History of serious adverse effects related to anaesthesia drugs like allergy
j)Pregnancy
k)History of seizures
l)History of any neuropsychiatric disorder
m)Patients on study drug infusion in last 12 hours
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the sedative and analgesic effects of Ketofol, Ketodex and Ketofen for dressing in burn patients by evaluating <br/ ><br>1.NRS pain scores <br/ ><br>2.Ramsay sedation score <br/ ><br>Timepoint: at the time of dressing
- Secondary Outcome Measures
Name Time Method To evaluate the effect of Ketofol , Ketodex and Ketofen on <br/ ><br>1.Hemodynamic profile (HR ,SBP , DBP ,MAP, Spo2, RR) <br/ ><br>2.Satisfaction of the patient <br/ ><br>3.Ease of dressing <br/ ><br>4.Any adverse effects <br/ ><br>Timepoint: at the time of dressing