To compare the effect of drugs ketofol and ketodex during oocyte pickup in in-vitro fertilisation procedures.
Phase 2
Completed
- Conditions
- Health Condition 1: Z30-Z39- Persons encountering health services in circumstances related to reproduction
- Registration Number
- CTRI/2022/12/047865
- Lead Sponsor
- Department of Anaesthesiology pain medicine and critical care
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
1.Age 20 to 40 years
2.ASA grade I -II patients scheduled for oocyte retrieval
Exclusion Criteria
1.Refusal for Consent
2.BMI >30
3.ASA grade III-IV Patients
4.Allergy to any of the study drugs
5.Patients with documented autonomic dysfunction
6.Uncontrolled systemic illness
7.Chronic diseases (Liver and kidney diseases, cancer, infectious diseases and autoimmune conditions)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To calculate mean pain scores intra-operatively and in the first 2 hours post-oocyte retrieval.Timepoint: To calculate mean pain scores intra-operatively and in the first 2 hours post-oocyte retrieval.
- Secondary Outcome Measures
Name Time Method 1)Intra and postoperative hemodynamic parameters will be noted. <br/ ><br>2)Intra and postoperative assessment of sedation level. <br/ ><br>3)Number of patients having moderate to severe pain at 30 minutes, 1 and 2 hours post-operatively. <br/ ><br>4)Total dose of intraoperative rescue bolus and postoperative rescue analgesia required. <br/ ><br>5)Duration of procedure and time till discharge will be calculated. <br/ ><br>6)To assess the incidence of PONV and other complications. <br/ ><br>7)Fertilisation rate <br/ ><br>8)Cleavage rateTimepoint: 1)Intra and postoperative hemodynamic parameters will be noted. <br/ ><br>2)Intra and postoperative assessment of sedation level. <br/ ><br>3)Number of patients having moderate to severe pain at 30 minutes, 1 and 2 hours post-operatively. <br/ ><br>4)Duration of procedure and time till discharge will be calculated. <br/ ><br>