sing either ketodex or ketofol to prevent distress while waking up from anaesthesia after transsphenoidal pituitary surgery
Not Applicable
- Conditions
- Health Condition 1: O- Medical and SurgicalHealth Condition 2: O- Medical and Surgical
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Adult patients (18-65 years)
2.Either gender
3.Scheduled for elective transsphenoidal pituitary surgeries.
4. American Society of Anaesthesiologists (ASA) Class I / II.
5.Body Mass Index (BMI) (22-28kg/m²)
Exclusion Criteria
1.Patients unable (legally incompetent) or unwilling to give consent.
2.Patient with difficult airway.
3.Previous history of psychiatric, anxiety or post-traumatic stress disorders.
4.History of allergy to study drugs.
5.Patient on sedative or hypnotic medication.
6.Patients with chronic pain or on painkiller.
7.Patients with severe hepatic or kidney disorders.
8.Patients having a history of thyrotoxicosis, hypertension or cardiac disorders.
9.Patients on chronic beta blockers.
10.Pregnant or breast feeding females
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sedation score (Riker Sedation -Agitation Score Scale)Timepoint: Every ten minutes for the first hour following surgery
- Secondary Outcome Measures
Name Time Method Emergence TimeTimepoint: Time between stoppage of sevoflurane to obeying verbal commands;Pain scores based on Visual Analogue ScaleTimepoint: Every ten minutes for the first hour following surgery;Time to achieve a Modified Aldrete Score of 9 or moreTimepoint: From the time of shifting to Post Anaesthesia care unit to achieving the score;Vital parameters like heart rate, systolic blood pressure, diastolic blood pressure & mean blood pressureTimepoint: Every ten minutes for the first hour following surgery;Adverse events like vomiting, nausea, bradycardia etc.Timepoint: Every ten minutes for the first hour following surgery