Comparison of the effect of Ketofol with Propofol on patients' vital sign changes during laparotomy
Phase 2
- Conditions
- Condition 1: Heart rate instability due to anesthesia. Condition 2: Blood pressure instability due to anesthesia.
- Registration Number
- IRCT2015021819037N6
- Lead Sponsor
- Investigator
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
Patients between 20 to 60 years of age who are candidate for laparotomy (including appendectomy, gastrectomy, cholecystectomy and other kinds of laparotomy) under general anesthesia and are in ASA class 1 (The American Society of Anesthesiologists Physical Status classification system): Normal healthy patients with no organic, physiologic, or psychiatric disturbance.
Exclusion criteria:
Patients who use cardiac or anti-hypertensive or analgesic or sedative agents, patients who are not NPO (nil per os), diabetic or pregnant patients.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mean heart rate. Timepoint: In 4 times: before induction, 3, 5 and 10 minutes after induction. Method of measurement: The monitor device.;Mean systolic pressure. Timepoint: In 4 times: before induction, 3, 5 and 10 minutes after induction. Method of measurement: The monitor device.;Mean diastolic pressure. Timepoint: In 4 times: before induction, 3, 5 and 10 minutes after induction. Method of measurement: The monitor device.
- Secondary Outcome Measures
Name Time Method