NL-OMON25488已完成不适用

A phase I/II study of active immunotherapy with autologous dendritic cells electrpoporated with TAT, REV and NEF encoding mRNA in HIV-I patients under stable HAART.

Erasmus MC, Rotterdam, Vrije Universiteit Brussel, BrusselK.Thielemans, MD, PhD Director Laboratory of Molecular and Cellular Therapy Medical School Vrije Universiteit BrusselLaarbeeklaan 103 B-1090 BrusselsTel: + 32 (0)2 477 45 69Fax: + 32 (0)2 477 45 68e-mail: Kris.Thielemans@vub.ac.be0 个研究点目标入组 17 人开始时间: 待定最近更新: 2024年2月28日

研究概览

简要总结

Allard S.D., Pletinckx K., Breckpot K., Heirman C., Michiels A., van Baalen C.A., Gruters R.A., Osterhaus A.D.M.E., Lacor P., Aerts J.L., Thielemans K. (2008) Functional T-cell responses generated by dendritic cells expressing the early HIV-1 proteins Tat, Rev and Nef. Vaccine 26, 3537-3541.

研究设计

研究类型: Interventional

入排标准

入选标准

•1. HIV-1 seropositive;
•2. >1 year on stable HAART;

排除标准

•1. Acute or serious illness <14 days before study entry;
•2. HIV viral load >50 copies/ml in 3 months before entry;

研究者

发起方

Erasmus MC, Rotterdam, Vrije Universiteit Brussel, BrusselK.Thielemans, MD, PhD Director Laboratory of Molecular and Cellular Therapy Medical School Vrije Universiteit BrusselLaarbeeklaan 103 B-1090 BrusselsTel: + 32 (0)2 477 45 69Fax: + 32 (0)2 477 45 68e-mail: Kris.Thielemans@vub.ac.be

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