Cyclosporin A (Neoral) for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) requiring repetitive administration of high-dose intravenous immunoglobuli
Not Applicable
- Conditions
- Chronic inflammatory demyelinating polyradiculoneuropathy
- Registration Number
- JPRN-UMIN000000674
- Lead Sponsor
- CIDP Study Group
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Not provided
Exclusion Criteria
1.polyneuropathy of other causes 2.multifocal motor neuropathy 3.positive for anti-MAG antibody 4.treated with prednisolone at a dose higher than 30 mg/day 5.previous history of cyclosporin A 6.neuron-Behcet 7.malignancy 8.chronic active inflammatory diseases 9.poor-controlled hypertension 10.congestive heart failure 11.liver cirrhosis 12.nephritic syndrome 13.hyperkalemia 14.gout 15.diabetes mellitus 16.pancreatitis 17.severe central nervous disorders 18.pregnancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method neurological symptom, frequency of high-dose intravenous immunoglobulin, toxicity
- Secondary Outcome Measures
Name Time Method