Predicting Transfers to Hemodialysis in Peritoneal Dialysis Patients Using the Surprise Question
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 2,019
- 试验地点
- 1
- 主要终点
- Performance measures of the modified surprise question answered by the physicians as a prediction instrument for transfer to hemodialysis of peritoneal dialysis patients in 6 months.
研究概览
简要总结
The investigators will assess the prediction performance of the modified Surprise Question (Will the participant be surprised if this patient transfers to hemodialysis in the next 6 months?) for identification of peritoneal dialysis at high risk of transfer to hemodialysis. The investigators will also assess the prediction performance of a modified mortality surprise question (Will the participant be surprised if this patient dies in the next 6 months?).
详细描述
Physicians and nurses will be asked two questions regarding each of their peritoneal dialysis patients:
- Will the participant be surprised if this patient transfers to hemodialysis in the next 6 months?
- Will the participant be surprised if this patient dies in the next 6 months?
Patients will be followed for 6 months for outcomes (with two extra months for ascertainment of outcomes).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Incident and prevalent PD population at Satellite Healthcare
排除标准
- •Age < 18 years
- •Patients already enrolled in hospice
- •Patients on PD training
- •Patients on backup hemodialysis
结局指标
主要结局
Performance measures of the modified surprise question answered by the physicians as a prediction instrument for transfer to hemodialysis of peritoneal dialysis patients in 6 months.
时间窗: at 6 months
次要结局
- Rate of hospitalizations in patients identified as high risk by the surprise question.(at 6 months)
- Performance of prediction model for transfer to HD developed from variables obtained at baseline.(at 0 months)
- Performance measures of the mortality SQ Responses of the physician and nurses to predict death(at 6 months)
- Performance measures of the modified SQ Responses of the nurses to predict Transfers to hemodialysis(at 6 months)
- Comparison of performance of baseline variables model to performance of the SQ model, and to a model that combines baseline variables and the SQ.(at 6 month)
- Proportion of patients identified as high risk who transition to HD.(At time of transfer to hemodialysis, for those who transfer to hemodialysis within the observation period, which is 6 months from response to the surprise question)
- Rate of peritonitis in patients identified as high risk by the surprise question.(at 6 months)
- Evaluating the agreement of assessments made by the primary nephrologist and the primary nurse of the patient(at baseline)
- Proportion of patients who transition to HD who (i) start Home HD and those who (ii) start HD with AVF/AVG - in the whole group and among those identified high or low risk by the surprise question.(At time of transfer to hemodialysis, for those who transfer to hemodialysis within the observation period, which is 6 months from response to the surprise question)
- Factors associated with predictions made by the MD and nurse.(at baseline)
研究者
Wael Hussein, MBBS
Senior Director of Clinical Research
Satellite Healthcare