Evaluation of the effect of selenium on patients with thyroid cancer treated with radioactive iodine

Phase 2

Recruiting

• Conditions: Thyroid cancer.; Neoplasm of uncertain behavior of thyroid gland; D44.0

• Registration Number: IRCT20201129049534N6
• Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 1 November 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Ages 20 to 65
Diagnosis of thyroid cancer by imaging, such as ultrasound, computed tomography, magnetic resonance imaging, and positron tomography (PET) scan

Exclusion Criteria

History of sialadenitis (inflammation of the salivary glands)
Sjogren's history
History of collagen vascular disease involving the salivary glands.
History of any salivary gland surgery
Follow a special diet in the last 3 months
Pregnancy and lactation
Patient dissatisfaction to participate in the study
Taking dietary supplements in the last 3 months
Suffering from certain diseases such as diseases caused by congenital diseases, immune system defects, etc.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Clinical status of salivary glands. Timepoint: At baseline and end of the study. Method of measurement: Ultrasound of major salivary glands (including examination of echogenicity, size, margin and contour).;C reactive Protein (CRP). Timepoint: At baseline and end of the study. Method of measurement: ELISA test.;Total oxidative stress. Timepoint: At baseline and end of the study. Method of measurement: Commercial diagnostic kit.;Total antioxidant capacity. Timepoint: At baseline and end of the study. Method of measurement: Commercial diagnostic kit.;Sense of taste. Timepoint: At baseline and end of the study. Method of measurement: Questionnaire designed by the researcher.;The rate of salivary gland secretion. Timepoint: At baseline and end of the study. Method of measurement: Questionnaire designed by the researcher.