Genetic Predisposition to Breast and Ovarian Cancer: Prospective Study of BRCAx Gene Mutation

Recruiting

• Conditions: Breast Cancers; Ovarian Cancers

• Registration Number: NCT03667417
• Lead Sponsor: Institut Paoli-Calmettes

Brief Summary

Cohort of subjects carrying a BRCA gene mutation: genetic predispositions to breast and ovarian cancers

Detailed Description

Cohort of subjects carrying a BRCA gene mutation: genetic predispositions to breast and ovarian cancers

Study Timeline

• Study Start: 1999-10-15
• Study First Submitted: 2018-09-10
• Study First Submitted QC: 2018-09-11
• Study First Posted: 2018-09-12
• Status Verified: 2020-06
• Last Update Submitted: 2020-06-30
• Last Update Posted: 2020-07-01
• Primary Completion: 2028-10-15
• Study Completion: 2028-10-15

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 5000

Inclusion Criteria

Not provided

Exclusion Criteria

1. A person of legal age subject to a legal protection measure, or unable to express consent.
2. Impossibility to submit to the follow-up of the test for geographical, social or psychological reasons

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of breast and / or ovarian cancer during subject lifetime	10 years	risk that a subject with a mutation develops breast and / or ovarian cancer during his lifetime, assessed by epidemiologic questionnaires (carcinologic events).

Trial Locations

Locations (1)

Institut Paoli-Calmettes; 🇫🇷 Marseille, France