Is a mixture of selected probiotic strains effective in improving eczema related symptoms?

Not Applicable

Completed

• Conditions: Atopic dermatitis; Skin and Connective Tissue Diseases

• Registration Number: ISRCTN10770381
• Lead Sponsor: Complife Italia Srl

Brief Summary

2021 Results article in https://pubmed.ncbi.nlm.nih.gov/33871363/ (added 13/08/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2019-04-19
• Study Start: 2020-03-05
• Last Update Posted: 24 August 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

1. Aged 18-50 years, with Phototype I to IV
2. Mild to moderate SCORAD (between 15 and 25)
3. Willingness to use during all the study period only the products to be tested
4. Subjects who have not been recently involved in any other similar study
5. Willingness to not use products likely to interfere with the products to be tested
6. Willingness to not vary the normal daily routine (i.e. lifestyle, physical activity, etc.)

Exclusion Criteria

1. Current antibiotic administration
2. Known history of chronic medical condition such as congenital heart disease, liver or kidney disease, or immune deficiency
3. Treatment with probiotics in the 6 months preceding enrollment
4. Treatment with steroids and antihistamines systemically in the three months prior to enrollment
5. Topical treatments with immunomodulators (tacrolimus or pimecrolimus) in the three months prior to enrollment
6. Acute or chronic infectious diseases
7. Subjects who has used sun-beds or self-tanning product for one month before the study or intend to use it during the present study

Study & Design

• Study Type: Interventional
• Study Design: Not specified