Daily probiotic supplementation and symptoms of allergic rhinitis

Not Applicable

Completed

• Conditions: Allergic Rhinitis; Respiratory - Other respiratory disorders / diseases; Inflammatory and Immune System - Allergies

• Registration Number: ACTRN12619001319167
• Lead Sponsor: Griffith University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-09-26
• Study Completion: 2021-02-19
• Last Update Posted: 28 November 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 160

Inclusion Criteria

• Be Male or female;
• Be aged between 18-65 years;
• Have more than 2 years history of moderate to severe persistent allergic rhinitis;
• Have moderate to severe allergic rhinitis as rated by the Allergic Rhinitis and its Impact
on Asthma (ARIA) criteria
• Have a positive radio-allergosorbent test (RAST) to Bermuda (couch) grass.

Exclusion Criteria

• Have non-allergic rhinitis
• Have a negative RAST to Bermuda grass
• Report consumption of probiotics or prebiotics in the previous 12 weeks;
• Report treatment with systemic corticosteroids in the previous 6 months;
• Have a history of respiratory diseases such as nasal polyposis and COPD ;
• Have a current respiratory viral infectious disease (common cold);
• Report current pregnancy or attempting to become pregnant;
• Report use of medications which effect salivary flow and components such as systemic
corticosteroids, diuretics and antidepressants;
• Allergic, sensitive or intolerant to (one of) the ingredients of the study product.

Study & Design

• Study Type: Interventional
• Study Design: Not specified