Probiotic supplementation in improving symptom control among children with Asthma

Not Applicable

• Conditions: Health Condition 1: J454- Moderate persistent asthmaHealth Condition 2: J459- Other and unspecified asthmaHealth Condition 3: J455- Severe persistent asthma

• Registration Number: CTRI/2023/10/058216
• Lead Sponsor: DrNiranjan Biswal

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 16 October 2023

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Children aged 6-18 years with moderate to severe asthma according to GINA criteria

Exclusion Criteria

Known cases of congenital or acquired immunodeficiency, cystic fibrosis and chronic pulmonary diseases, Alpha 1 antitrypsin deficiency, congenital heart disease, children with acute exacerbation, active respiratory infection.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess the effect of probiotic supplementation in symptom control among children with moderate to severe asthma using GINA asthma symptom control criteriaTimepoint: 0week 4weeks 8weeks 12weeks

Secondary Outcome Measures

Name	Time	Method
To assess the effect of probiotic supplementation in reducing the number & severity of acute exacerbations in children with moderate & severe asthma.Timepoint: 0week 4weeks 8weeks 12weeks;To assess the effect of Probiotic supplementation on Absolute Eosinophilic Count in children with moderate & severe asthma.Timepoint: 0week 12week;To assess the effect of Probiotic Supplementation on FEV1, FVC & FEV1/FVC in children with moderate and severe asthma.Timepoint: 0week 12week;To assess the effect of Probiotic supplementation on inflammatory markers IL-4, IL-5 & IL-13 in children with moderate and severe asthma .Timepoint: 0week 12week