NCT03211650已完成4 期
Efficacy of Intra-articular Injection of Combined Hyaluronic Acid and Platelet-rich Plasma in Knee Degenerative Joint Disease
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 174
- 试验地点
- 2
- 主要终点
- WOMAC score
研究概览
简要总结
The purpose of this study is to evaluate the efficacy of intra-articular injections of combined hyaluronic acid and platelet-rich plasma in knee degenerative joint disease in improving joint function and reducing pain.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 30 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
hyaluronic acid + platelet-rich plasma
Experimental
Intra-articular injections of hyaluronic acid combined with platelet-rich plasma
干预措施: hyaluronic Acid + platelet-rich plasma (Drug)
platelet-rich plasma
Active Comparator
Intra-articular injections of platelet-rich plasma
干预措施: platelet-rich plasma (Drug)
hyaluronic acid
Active Comparator
Intra-articular injections of hyaluronic acid
干预措施: hyaluronic acid (Drug)
结局指标
主要结局
WOMAC score
时间窗: 6 months after the first intra-articular injection
Comparison of WOMAC total score among three treatment arms
次要结局
未报告次要终点
研究者
Pietro Randelli, MD
Full Professor
University of Milan
研究点 (2)
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