Frequency of Shivering Among Patient Treaed With IV Tramadol Versus Iv Ketamine in Prevention of Post Spinal Anesthesia Undergoing Cesarean Section: Rendomiced Control Trial
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 250
- 试验地点
- 1
- 主要终点
- Shivering
研究概览
简要总结
*Ketamine:* Ketamine is a medication that can help reduce shivering by blocking certain nerve signals in the brain. It's like a "nerve blocker" that helps calm down the body's shivering response.
- *Tramadol:* Tramadol is a pain medication that can also help reduce shivering. It works by affecting the brain's temperature regulation centers, which helps to reduce the shivering response.
详细描述
Post-spinal shivering is when a patient starts shaking or shivering after receiving spinal anesthesia. This can be uncomfortable and even scary for the patient.
Using ketamine and tramadol to reduce post-spinal shivering can have several benefits, including:
- Reduced discomfort and anxiety for the patient
- Improved patient satisfaction
- Reduced need for additional medications or interventions
- Faster recovery times
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Pateint for elective cesarean section
- •Age 18 to 40 years
- •ASA 1 and 2
排除标准
- •ASA 2 and 3
- •Cesarean section requiring general anesthesia
- •Hypersensitivity to Ketamine, Tramadol and Opiods
- •History of cardiovascular disease
研究组 & 干预措施
Group T
Group T receive Inj: Tramadol
干预措施: Tramadol (Drug)
Group K
Group K receive Inj: ketamine
干预措施: Ketamine only (Drug)
结局指标
主要结局
Shivering
时间窗: 20 minutes to 12 hours
Scale validated by crossley and mahajan Grade 0: No shivering Grade 1: Piloerection, peripheral vasoconstriction, peripheral cyanosis, or mild fasciculation of the face or neck, but no visible muscle activity Grade 2: Visible muscle activity in one muscle group Grade 3: Visible muscle activity in more than one muscle group Grade 4: Gross muscle activity involving the entire body
次要结局
未报告次要终点
研究者
Nazish Kanwal
Principal Investigator
Liaquat National Hospital & Medical College