Effect of Cranberry Extract on the Urinary System

Completed

• Conditions: Antibiotic Reaction; Cystitis; Urinary Tract Disease
• Interventions: Dietary Supplement: Cranberry; Drug: Fosfomycin

• Registration Number: NCT05260554
• Lead Sponsor: Kırklareli University

Brief Summary

In this study, we will try to emphasize the effects of using cranberry tablets, which is an alternative to antibiotic therapy, during uncomplicated urinary tract infections (only urinary tract, bladder and kidney infections did not).

Detailed Description

This study was Istanbul Kartal Dr. Lütfi Kırdar Training and Research Hospital Emergency Medicine Clinic and Kırklareli Training and Research Hospital Emergency Service and Internal Medicine Polyclinic. Our study; includes patients who applied to the Emergency Department and Internal Medicine outpatient clinic with the complaint of dysuria and had normal WBC, CRP, urea, and creatinine values in their analysis, and leukocyturia was found in the urine test. Two options were offered in the treatment to these patients. Vaccinium Macrocarpon Aiton preparation or fosfomycin was given for seven days. The patients were asked whether their complaints had decreased according to the Lykert-Type verbal scale at the time of admission and on the first, third, and seventh days. When the treatment was finished, leukocytes were checked in the urinalysis. This outcome was compared between the 2 treatment options. We also noted whether nausea.

Study Timeline

• Study Start: 2022-01-26
• Status Verified: 2022-02
• Primary Completion: 2022-02-18
• Study Completion: 2022-02-18
• Study First Submitted: 2022-02-18
• Study First Submitted QC: 2022-02-18
• Last Update Submitted: 2022-02-18
• Study First Posted: 2022-03-02
• Last Update Posted: 2022-03-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 2

Inclusion Criteria

• Older than 18
• who have urinary tract inflammation
• who haven't kidney dissease previous

Exclusion Criteria

• Younger than 18
• Who have kidney inflammation
• Pregnant patients
• Who have blood test abnormal (WBC, Ure, Creatin, CRP high level)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
using cranberry extract	Cranberry	The patients in this group; took 7 days (1 tablet each day) of cranberry tablets.
using fosfomycin	Fosfomycin	The patients in this group; have been prescribed fosfomycin for 7 days (3 doses, two days apart).

Primary Outcome Measures

Name	Time	Method
Treatment time	7 days	After 7 days of treatment, the 2 treatment options were compared with each other.

Trial Locations

Locations (1)

Oya Guven, MD; 🇹🇷 Kirklareli, Center, Turkey