Fosfomycin
- Generic Name
- Fosfomycin
- Brand Names
- Monurol
- Drug Type
- Small Molecule
- Chemical Formula
- C3H7O4P
- CAS Number
- 23155-02-4
- Unique Ingredient Identifier
- 2N81MY12TE
- Background
Fosfomycin was discovered in 1969 by scientists at the Spanish Penicillin and Antibiotics Company and is produced by Streptomyces fradiae. It may also be produced synthetically and is commercially available as the disodium salt for intravenous administration and as the calcium or trometamol salt for oral administration. In terms of chemical structure, fosfom...
- Indication
Fosfomycin is indicated for the treatment of uncomplicated cases of cystitis caused by susceptible strains of Escherichia coli and Enterococcus faecalis. Fosfomycin is not officially indicated for the treatment of pyelonephritis or perinephric abscess, although there have been reported cases of off-label usage in these situations.
- Associated Conditions
- Complicated Urinary Tract Infection, Uncomplicated Urinary Tract Infections caused by E. coli, Uncomplicated Urinary Tract Infections caused by Enterococcus faecalis
- Associated Therapies
- -
COMPARISON OF NITROFURANTOIN WITH FOSFOMYCIN in TREATING CYSTITIS IN WOMEN
- Conditions
- Interventions
- First Posted Date
- 2024-07-24
- Last Posted Date
- 2024-07-24
- Lead Sponsor
- Shalamar Institute of Health Sciences
- Target Recruit Count
- 392
- Registration Number
- NCT06518291
Therapeutic Options for CRAB
- Conditions
- Interventions
- First Posted Date
- 2024-06-03
- Last Posted Date
- 2024-06-17
- Lead Sponsor
- Clinical Hospital Centre Zagreb
- Target Recruit Count
- 108
- Registration Number
- NCT06440304
Fosfomycin Versus Standard of Care in Children With Antibiotic-resistant Urinary Tract Infections
- Conditions
- Interventions
- First Posted Date
- 2023-02-01
- Last Posted Date
- 2024-06-06
- Lead Sponsor
- University of Sydney
- Target Recruit Count
- 300
- Registration Number
- NCT05709028
- Locations
- 🇦🇺
Sydney Childrens Hospital, Sydney, New South Wales, Australia
🇦🇺The Children's Hospital at Westmead, Sydney, New South Wales, Australia
🇦🇺Royal Childrens Hospital, Melbourne, Victoria, Australia
Effect of Cranberry Extract on the Urinary System
- Conditions
- Interventions
- First Posted Date
- 2022-03-02
- Last Posted Date
- 2022-03-02
- Lead Sponsor
- Kırklareli University
- Target Recruit Count
- 2
- Registration Number
- NCT05260554
- Locations
- 🇹🇷
Oya Guven, MD, Kirklareli, Center, Turkey
EXtended Use of FOsfomycin for the Treatment of CYstitis in Primary Care
- Conditions
- Interventions
- First Posted Date
- 2022-02-24
- Last Posted Date
- 2022-03-15
- Lead Sponsor
- MJM Bonten
- Target Recruit Count
- 13
- Registration Number
- NCT05254808
- Locations
- 🇳🇱
UMC Utrecht, Utrecht, Netherlands
🇳🇱Medisch Centrum Heuvelrug, Doorn, Utrecht, Netherlands
🇳🇱Huisartsenpraktijk Binnenstad, Utrecht, Netherlands
Efficacy and Safety of Intravenous Fosfomycin in Prosthetic Joint Infection
- First Posted Date
- 2022-01-27
- Last Posted Date
- 2022-01-27
- Lead Sponsor
- Charite University, Berlin, Germany
- Target Recruit Count
- 226
- Registration Number
- NCT05211011
- Locations
- 🇩🇪
Universitätsmedizin Mainz, Mainz, Germany
🇩🇪Universitätsklinikum Bonn, Bonn, Germany
🇩🇪Städtisches Klinikum Dresden, Dresden, Germany
Bearberry in the Treatment of Cystitis
- First Posted Date
- 2021-09-24
- Last Posted Date
- 2021-09-24
- Lead Sponsor
- University of Pecs
- Target Recruit Count
- 504
- Registration Number
- NCT05055544
- Locations
- 🇭🇺
Institute for Translational Medicine, University of Pécs, Pécs, Hungary
The Combined Antibiotic Therapy for Carbapenem Resistant Klebsiella Pneumoniae
- Conditions
- Interventions
- First Posted Date
- 2019-05-15
- Last Posted Date
- 2019-05-15
- Lead Sponsor
- Shanghai 10th People's Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT03950544
- Locations
- 🇨🇳
Shanghai 10th people's hospital, Shanghai, Shanghai, China
the Use of Fosfomycin as a Single Dose Oral Treatment of Asymptomatic Bacteriuria
- First Posted Date
- 2018-06-07
- Last Posted Date
- 2018-06-07
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 88
- Registration Number
- NCT03548129
Efficacy and Safety of Intravenous Fosfomycin in Prosthetic Joint Infection
- First Posted Date
- 2017-08-24
- Last Posted Date
- 2018-04-19
- Lead Sponsor
- Pro-Implant Foundation
- Target Recruit Count
- 224
- Registration Number
- NCT03260010
- Locations
- 🇩🇪
Charité - Univeristätsmedizin, Berlin, Germany
Drug Development Updates
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