Pivmecillinam
- Generic Name
- Pivmecillinam
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C21H33N3O5S
- CAS Number
- 32886-97-8
- Unique Ingredient Identifier
- 1WAM1OQ30B
- Background
Pivmecillinam is a mecillinam prodrug, a pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa. It is active against gram-negative organisms and used as for amdinocillin. [PubChem]
- Indication
Used to treat infections due to mecillinam-sensitive organisms such as urinary tract infections, salmonellosis and typhoid fever.
- Associated Conditions
- Urinary tract infection caused by E. coli, Urinary tract infection caused by enterobacteria, Urinary tract infection caused by klebsiella, Urinary tract infection caused by proteus
- Associated Therapies
- -
Clinical Trial Testing Whether Targeted Antibiotic Prophylaxis Can Reduce Infections After Cystectomy Compared to Empiric Prophylaxis
Phase 4
Recruiting
- Conditions
- CystectomyBladder Cancer Requiring CystectomyPostoperative InfectionsAntibiotic ProphylaxisIleal Conduit
- Interventions
- First Posted Date
- 2024-11-29
- Last Posted Date
- 2025-01-09
- Lead Sponsor
- Rigshospitalet, Denmark
- Target Recruit Count
- 248
- Registration Number
- NCT06709196
- Locations
- 🇩🇰
Department of Urology, Aalborg University Hospital, Aalborg, Denmark
🇩🇰Department of Urology, Aarhus University Hospital, Aarhus, Denmark
🇩🇰Department of Urology, Rigshospitalet, Copenhagen, Denmark
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