Sulfamethoxazole
- Generic Name
- Sulfamethoxazole
- Brand Names
- Bactrim, Septra, Sulfatrim
- Drug Type
- Small Molecule
- Chemical Formula
- C10H11N3O3S
- CAS Number
- 723-46-6
- Unique Ingredient Identifier
- JE42381TNV
- Background
Sulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria. It is generally given in combination with trimethoprim, which inhibits a sequential step in bacterial folic acid synthesis - these agents work synergistically to block two consecutive steps in the biosynthesis of nucleic acids and pr...
- Indication
Sulfamethoxazole is indicated in combination with trimethoprim, in various formulations, for the following infections caused by bacteria with documented susceptibility: urinary tract infections, acute otitis media in pediatric patients (when clinically indicated), acute exacerbations of chronic bronchitis in adults, enteritis caused by susceptible Shigella, ...
- Associated Conditions
- Acute Exacerbation of Chronic Bronchitis (AECB) caused by susceptible bacteria, Acute Otitis Media caused by susceptible bacteria, Brucellosis, Dysentery, Bacillary, Nocardiosis, Pneumocystis Jirovecii Pneumonia, Urinary Tract Infection caused by susceptible bacteria, Susceptible Cholera, Susceptible Enteritis infectious caused by Shigella flexneri, Susceptible Enteritis infectious caused by Shigella sonnei, Susceptible Travelers' Diarrhea caused by Enterotoxigenic E. Coli (ETEC) Infection
- Associated Therapies
- -
Collaborative Urological Prosthetics Investigation Directive Research Group
- Conditions
- Interventions
- First Posted Date
- 2021-10-29
- Last Posted Date
- 2024-02-07
- Lead Sponsor
- University of Chicago
- Target Recruit Count
- 800
- Registration Number
- NCT05100654
- Locations
- 🇺🇸
University of Chicago, Chicago, Illinois, United States
Or v IV Antibiotics for Infection
- Conditions
- Interventions
- First Posted Date
- 2021-01-26
- Last Posted Date
- 2021-01-26
- Lead Sponsor
- Rothman Institute Orthopaedics
- Target Recruit Count
- 308
- Registration Number
- NCT04723940
- Locations
- 🇺🇸
Rothman Orthopaedic Institute, Philadelphia, Pennsylvania, United States
A Non-Interventional Safety Study of Balsamic Bactrim
- First Posted Date
- 2016-09-16
- Last Posted Date
- 2017-11-07
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 52
- Registration Number
- NCT02902640
- Locations
- 🇵🇪
Clinica San Borja; Instituto de Enfermedades Respiratorias EFEH, Lima, Peru
🇵🇪Clinica de Especialidades Medicas, Lima, Peru
🇵🇪Centro de Investigaciones Medicas/Hospital Maria Auxiliadora, San Juan de Miraflores, Peru
A Safety Study of Balsamic Bactrim in Pediatric Participants With Acute Bronchitis
- First Posted Date
- 2016-08-26
- Last Posted Date
- 2019-12-13
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 51
- Registration Number
- NCT02879981
- Locations
- 🇵🇪
Hospital Emergencias Pediatricas; Unidad de Investigación Pediátrica, La Victoria, Peru
🇵🇪Clínica Anglo Americana-CENTRO DE INVESTIGACION PEDIATRIA CAA, San Isidro, Peru
🇵🇪Clinica Internacional, Sede San Borja; Unidad de Investigacion de Clínica Internacional, Lima, Peru
Sulfamethoxazole for the Treatment of Primary PREPL Deficiency
- Conditions
- Interventions
- First Posted Date
- 2015-12-29
- Last Posted Date
- 2015-12-29
- Lead Sponsor
- Universitair Ziekenhuis Brussel
- Target Recruit Count
- 15
- Registration Number
- NCT02640443
Antibiotic Use Following Distal and Mid-shaft Hypospadias Repair
- First Posted Date
- 2015-11-01
- Last Posted Date
- 2018-11-05
- Lead Sponsor
- Medical College of Wisconsin
- Target Recruit Count
- 67
- Registration Number
- NCT02593903
- Locations
- 🇺🇸
Children's Hospital of Wisconsin, Milwaukee, Wisconsin, United States
Prevention of Catheter-Associated Urinary Tract Infection in Incontinence and Reconstructive Pelvic Surgery Patients
- Conditions
- Interventions
- First Posted Date
- 2010-04-22
- Last Posted Date
- 2017-10-18
- Lead Sponsor
- The Cleveland Clinic
- Target Recruit Count
- 52
- Registration Number
- NCT01108757
- Locations
- 🇺🇸
Cleveland Clinic Foundation, Cleveland, Ohio, United States
Prospective Randomized Trial of Bactrim on 7 Day Outcome in Patients With Uncomplicated Abscesses
- First Posted Date
- 2009-09-09
- Last Posted Date
- 2010-03-09
- Lead Sponsor
- 59th Medical Wing
- Target Recruit Count
- 212
- Registration Number
- NCT00973765
- Locations
- 🇺🇸
Wilford Hall Medical Center, Lackland Air Force Base, Texas, United States
Trial of Antibiotic Treatment for Skin Abscess in Patients at Risk for Methicillin-Resistant Staphylococcus Aureus (MRSA) Infection
- First Posted Date
- 2009-01-27
- Last Posted Date
- 2017-06-09
- Lead Sponsor
- 59th Medical Wing
- Target Recruit Count
- 31
- Registration Number
- NCT00829686
- Locations
- 🇺🇸
Wilford Hall Medical Center, Lackland Air Force Base, Texas, United States
S0333 Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
- Conditions
- Interventions
- Biological: filgrastimDrug: cyclophosphamideDrug: cytarabineDrug: daunorubicinDrug: dexamethasoneDrug: doxorubicinDrug: leucovorinDrug: mercaptopurineDrug: methotrexateDrug: mitoxantroneDrug: AsparaginaseDrug: prednisoneDrug: thioguanineDrug: vincristineRadiation: radiation therapyDrug: allopurinolDrug: bactrim
- First Posted Date
- 2005-05-04
- Last Posted Date
- 2015-03-25
- Lead Sponsor
- SWOG Cancer Research Network
- Target Recruit Count
- 79
- Registration Number
- NCT00109837
- Locations
- 🇺🇸
Providence Saint Joseph Medical Center - Burbank, Burbank, California, United States
🇺🇸Gibbs Regional Cancer Center at Spartanburg Regional Medical Center, Spartanburg, South Carolina, United States
🇺🇸Minor and James Medical, PLLC, Seattle, Washington, United States
Drug Development Updates
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