Cefuroxime

Generic Name
Cefuroxime
Brand Names
Ceftin
Drug Type
Small Molecule
Chemical Formula
C16H16N4O8S
CAS Number
55268-75-2
Unique Ingredient Identifier
O1R9FJ93ED
Background

Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.

Indication

For the treatment of many different types of bacterial infections such as bronchitis, sinusitis, tonsillitis, ear infections, skin infections, gonorrhea, and urinary tract infections.

Associated Conditions
Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB), Animal bite, Bacterial Infections, Bone and Joint Infections, Impetigo, Lower Respiratory Tract Infection (LRTI), Lyme Disease, Maxillary Sinusitis, Meningitis, Neisseria Gonorrhoeae Infection, Septicemia, Skin and Subcutaneous Tissue Bacterial Infections, Urinary Tract Infection, Bacterial otitis media, Mild Streptococcal pharyngitis, Mild Streptococcal tonsillitis, Moderate Streptococcal pharyngitis, Moderate Streptococcal tonsillitis
Associated Therapies
-

Clinical Trial Testing Whether Targeted Antibiotic Prophylaxis Can Reduce Infections After Cystectomy Compared to Empiric Prophylaxis

First Posted Date
2024-11-29
Last Posted Date
2024-12-16
Lead Sponsor
Rigshospitalet, Denmark
Target Recruit Count
248
Registration Number
NCT06709196
Locations
🇩🇰

Department of Urology, Aalborg University Hospital, Aalborg, Denmark

🇩🇰

Department of Urology, Aarhus University Hospital, Aarhus, Denmark

🇩🇰

Department of Urology, Rigshospitalet, Copenhagen, Denmark

and more 2 locations

Clinical Trial Comparing Oral Versus Intravenous Cefuroxime in Pregnant Women With Pyelonephritis

Phase 4
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-07-30
Last Posted Date
2024-07-30
Lead Sponsor
Hospital de Clinicas de Porto Alegre
Target Recruit Count
100
Registration Number
NCT06527560
Locations
🇧🇷

HCPA, Porto Alegre, RS, Brazil

Standard Versus Prolonged Antibiotic Prophylaxis After Pancreatoduodenectomy (SPARROW)

Phase 4
Recruiting
Conditions
Interventions
First Posted Date
2023-03-24
Last Posted Date
2024-10-21
Lead Sponsor
Leiden University Medical Center
Target Recruit Count
344
Registration Number
NCT05784311
Locations
🇳🇱

Leiden University Medical Center, Leiden, Zuid Holland, Netherlands

🇳🇱

Amsterdam University Medical Center, Amsterdam, Netherlands

🇳🇱

Amphia Ziekenhuis, Breda, Netherlands

and more 8 locations

Colo-Pro_2: Bolus-continuous Infusion Cefuroxime Prophylaxis for the Prevention of Infections After Colorectal Surgery

Phase 2
Recruiting
Conditions
Interventions
First Posted Date
2022-11-08
Last Posted Date
2024-05-08
Lead Sponsor
University of Leeds
Target Recruit Count
180
Registration Number
NCT05609240
Locations
🇬🇧

TheUniversity of Birmingham, Birmingham, West Midlands, United Kingdom

🇬🇧

Aneurin Bevan University Health Board, Newport, United Kingdom

🇬🇧

Leeds Teaching Hospitals, Leeds, West Yorkshire, United Kingdom

Population Pharmacokinetics, Effectiveness and Safety of Cefuroxime in Neonates

Recruiting
Conditions
First Posted Date
2022-05-24
Last Posted Date
2022-05-24
Lead Sponsor
Shandong University
Target Recruit Count
100
Registration Number
NCT05388747
Locations
🇨🇳

Tianjin Central Hospital of Gynecology Obstetrics, Tianjin, Tianjin, China

Qingfei Granule for the Treatment of the Pediatric Acute Upper Respiratory Tract Infection With Bacterial Infection

First Posted Date
2020-07-21
Last Posted Date
2022-11-15
Lead Sponsor
Zhong Wang
Target Recruit Count
60
Registration Number
NCT04479657
Locations
🇨🇳

Dongfang Hospital, Beijing, Beijing, China

Pharmacokinetics of Amikacin and Cefuroxime in Critically Ill Patients.

First Posted Date
2020-07-14
Last Posted Date
2022-09-10
Lead Sponsor
Radboud University Medical Center
Target Recruit Count
40
Registration Number
NCT04470973
Locations
🇳🇱

Radboudumc intensive care, Nijmegen, Netherlands

24 Vs 48 Hours of Cefazolin or Cefuroxime as Prophylaxis

First Posted Date
2020-03-11
Last Posted Date
2023-04-11
Lead Sponsor
Saud Al Babtain Cardiac Center
Target Recruit Count
568
Registration Number
NCT04303390
Locations
🇸🇦

Saud AlBabtain Cardiac Center, Dammam, Eastern Province, Saudi Arabia

Intracameral Levofloxacin (0.5%) vs Intracameral Cefuroxime

First Posted Date
2019-12-26
Last Posted Date
2020-09-21
Lead Sponsor
National University of Malaysia
Target Recruit Count
138
Registration Number
NCT04212078
Locations
🇲🇾

UKM Medical Centre, Kuala Lumpur, Wilayah Persekutuan, Malaysia

Pharmacokinetics of Post Operative Cefuroxime in Infants Undergoing Cardiac Surgery

Withdrawn
Conditions
First Posted Date
2016-07-29
Last Posted Date
2019-01-10
Lead Sponsor
Alder Hey Children's NHS Foundation Trust
Registration Number
NCT02850250
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