Fosfomycin
- Generic Name
- Fosfomycin
- Brand Names
- Monurol
- Drug Type
- Small Molecule
- Chemical Formula
- C3H7O4P
- CAS Number
- 23155-02-4
- Unique Ingredient Identifier
- 2N81MY12TE
- Background
Fosfomycin was discovered in 1969 by scientists at the Spanish Penicillin and Antibiotics Company and is produced by Streptomyces fradiae. It may also be produced synthetically and is commercially available as the disodium salt for intravenous administration and as the calcium or trometamol salt for oral administration. In terms of chemical structure, fosfom...
- Indication
Fosfomycin is indicated for the treatment of uncomplicated cases of cystitis caused by susceptible strains of Escherichia coli and Enterococcus faecalis. Fosfomycin is not officially indicated for the treatment of pyelonephritis or perinephric abscess, although there have been reported cases of off-label usage in these situations.
- Associated Conditions
- Complicated Urinary Tract Infection, Uncomplicated Urinary Tract Infections caused by E. coli, Uncomplicated Urinary Tract Infections caused by Enterococcus faecalis
- Associated Therapies
- -
Culture-guided Antimicrobial Prophylaxis in Men Undergoing Prostate Biopsy.
- Conditions
- Interventions
- First Posted Date
- 2017-07-24
- Last Posted Date
- 2022-05-10
- Lead Sponsor
- Radboud University Medical Center
- Target Recruit Count
- 1538
- Registration Number
- NCT03228108
- Locations
- 🇳🇱
Zuyderland Hospital, Sittard, Netherlands
🇳🇱Amphia Hospital, Breda, Netherlands
🇳🇱Radboud University Medical Center, Nijmegen, Netherlands
Observational Follow-up Study of REGATTA
- Conditions
- Interventions
- First Posted Date
- 2017-06-05
- Last Posted Date
- 2019-11-27
- Lead Sponsor
- University Medical Center Goettingen
- Target Recruit Count
- 398
- Registration Number
- NCT03176563
- Locations
- 🇩🇪
General Practice Koch, Göttingen, Germany
🇩🇪General Practice Kolb, Göttingen, Germany
🇩🇪Institute of General Medicine, MHH Hannover, Hannover, Germany
Reducing Antibiotic Use for Uncomplicated Urinary Tract Infection in General Practice by Treatment With Uva Ursi (UU)- a Comparative Effectiveness Trial
- Conditions
- Interventions
- First Posted Date
- 2017-05-12
- Last Posted Date
- 2019-11-27
- Lead Sponsor
- University Medical Center Goettingen
- Target Recruit Count
- 398
- Registration Number
- NCT03151603
- Locations
- 🇩🇪
General Practice Schelp, Bremen, Germany
🇩🇪General Practice Aden, Braunschweig, Germany
🇩🇪General Practice Stegemann, Wunstorf, Germany
A Phase III Safety Study of Ferumoxytol Compared to Ferric Carboxymaltose for the Treatment of Iron Deficiency Anemia (IDA)
- First Posted Date
- 2016-03-01
- Last Posted Date
- 2023-07-25
- Lead Sponsor
- AMAG Pharmaceuticals, Inc.
- Target Recruit Count
- 2014
- Registration Number
- NCT02694978
- Locations
- 🇵🇷
Clinical Trial Site, Ponce, Puerto Rico
🇺🇸AMAG Pharmaceuticals, Inc., Waltham, Massachusetts, United States
PK/PD and Safety/Tolerability of Two Dosing Regimens of Oral Fosfomycin Tromethamine in Healthy Adults
- First Posted Date
- 2015-10-07
- Last Posted Date
- 2019-07-30
- Lead Sponsor
- Vance Fowler, M.D.
- Target Recruit Count
- 19
- Registration Number
- NCT02570074
- Locations
- 🇺🇸
University of Illinois at Chicago, Chicago, Illinois, United States
Study Comparing Nitrofurantoin to Fosfomycin for Acute Urinary Tract Infection in Women
- First Posted Date
- 2013-10-21
- Last Posted Date
- 2017-05-02
- Lead Sponsor
- University Hospital, Geneva
- Target Recruit Count
- 600
- Registration Number
- NCT01966653
- Locations
- 🇮🇱
Tel Aviv University, Tel Aviv, Israel
🇵🇱Lodz University Hospital, Lodz, Poland
🇨🇭University Hospitals of Geneva, Geneva, Switzerland
Single Dose Monurol for Treatment of Acute Cystitis
- First Posted Date
- 2009-09-15
- Last Posted Date
- 2023-06-05
- Lead Sponsor
- University of Washington
- Target Recruit Count
- 300
- Registration Number
- NCT00976963
- Locations
- 🇺🇸
University of Washington, Seattle, Washington, United States
Drug Development Updates
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