Molecular mechanisms involved in the protective role of olive oil in the development of atherosclerotic processes

Completed

• Conditions: Cardiovascular risk; Circulatory System

• Registration Number: ISRCTN53283428
• Lead Sponsor: Spanish Olive Oil Producers Association (Patrimonio Comunal Olivarero) (Spain)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2009-07-28
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

Healthy volunteers aged 20 - 50 years old, either sex

Exclusion Criteria

1. Intake of antioxidant supplements
2. Intake of acetosalicylic acid
3. Intake of any other drug with established antioxidative properties
4. Athletes with high physical activity (greater than 3000 kcal per week in leisure-time physical activity)
5. Obesity (body mass index [BMI] greater than 30 kg/m^2)
6. Hypercholestrolaemia greater than 8.0 mmol per litre or dyslipidaemia therapy indication
7. Diabetes
8. Hypertension (systolic blood pressure [SBP] greater than 140 mmHg, diastolic blood pressure [DBP] greater than 90 mmHg)
9. Multiple allergies
10. Coeliac or other intestinal diseases
11. Any condition that limits the mobility of the subject making study visits impossible
12. Life-threatening illnesses such as cancer or a severe disease with a less than 3-year expectancy
13. Other diseases or conditions that could worsen adherence to the measurements or treatments
14. Vegetarians and people following special diets
15. Alcoholism or other drug addiction

Study & Design

• Study Type: Interventional
• Study Design: Not specified