Postanaesthetic Outcome and Assessment of Fatigue in Day-surgery Laparoscopic Cholecystectomy
Overview
- Phase
- Phase 4
- Intervention
- Desflurane
- Conditions
- Fatigue
- Sponsor
- Sykehuset Telemark
- Enrollment
- 130
- Locations
- 1
- Primary Endpoint
- Incidence and severity of fatigue after anaesthesia based on propofol or desflurane
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
The purpose of this study is to establish validated outcome measures for Postoperative Fatigue and Postoperative nausea, and to compare clinical impact of postanaesthetic symptoms during first week after Propofol or Desflurane based anaesthesia.
Investigators
Torkjell Nostdahl
MD, Anaesthesiologist
Sykehuset Telemark
Eligibility Criteria
Inclusion Criteria
- •Patients scheduled for day-surgery laparoscopic cholecystectomy
- •The patient is able to read and comprehend Norwegian language
- •The patient is cognitive adequate and able to fill in survey forms
- •The patient has read and signed patient information form
Exclusion Criteria
- •Serious illness (ASA 3-4)
- •Pregnancy or suspected pregnancy
- •Breastfeeding women
- •Contraindications to use of NSAIDs
- •Serious allergic reaction to anaesthetics
- •Allergy towards egg, soya or peanuts
- •Known or suspected Malignant Hyperthermia or Porphyria
- •Fatigue-related diagnosis
- •Recently received adjuvant therapy (chemotherapy, radiotherapy)
- •Severe chronic pain
Arms & Interventions
Desflurane
Patients will receive Desflurane to provide sleep during anaesthesia for laparoscopic cholecystectomy. Analgesia will be provided by remifentanil.
Intervention: Desflurane
Propofol
Patients will receive Propofol to provide sleep during anaesthesia for laparoscopic cholecystectomy. Analgesia will be provided by remifentanil.
Intervention: Propofol
Outcomes
Primary Outcomes
Incidence and severity of fatigue after anaesthesia based on propofol or desflurane
Time Frame: Within the first week postoperatively
Fatigue scales; Chalder Fatigue Scale and Incidence-Consequence Fatigue Scale. Measure points; 1st, 3rd, 6th and 30th day postoperatively.
Secondary Outcomes
- Incidence and severity of postoperative nausea after anaesthesia based on propofol or desflurane(Within the first week postoperatively)
- Fatigue scale validation(See under "Description":)