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Clinical Trials/NCT03982758
NCT03982758
Unknown
Not Applicable

Acute Effect of Isometric Physical Exercise on Blood Pressure in Patients With Controlled Hypertension

Instituto de Cardiologia do Rio Grande do Sul1 site in 1 country80 target enrollmentDecember 9, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Arterial Hypertension
Sponsor
Instituto de Cardiologia do Rio Grande do Sul
Enrollment
80
Locations
1
Primary Endpoint
blood pressure
Last Updated
4 years ago

Overview

Brief Summary

International recommendations advocate dynamic or isometric strength training as an adjunct to aerobic exercise. Due to a lack of consensus, this research addresses the acute effects of isometric exercises by handgrip or lower limb isometry as a hypotensive strategy in hypertensive adults.

Detailed Description

This study is characterized as a randomized, controlled and blinded clinical trial for the evaluators and carried out integrally in the Laboratory of Clinical Investigation (LIC) of the Cardiology Institute of Rio Grande do Sul / University Foundation of Cardiology (ICFUC). The project follows all recommendations proposed by the CONSORT Statement. The study will consist of individuals of both genders, aged between 40 and 70 years who have blood pressure above 120mmhg by 80mhg. The participants, after signing the informed consent, answered a questionnaire that will evaluate the habitual level of physical activity and will be submitted to isometric exercises of palmar grip or quadriceps muscle. Pre- and post-exercise blood pressure will be monitored through the ambulatory blood pressure monitoring (ABPM) method.

Registry
clinicaltrials.gov
Start Date
December 9, 2019
End Date
March 18, 2022
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Instituto de Cardiologia do Rio Grande do Sul
Responsible Party
Principal Investigator
Principal Investigator

Patricia Caetano

principal investigador

Instituto de Cardiologia do Rio Grande do Sul

Eligibility Criteria

Inclusion Criteria

  • Controlled hypertensive patients (use of medication) sedentary or physically inactive

Exclusion Criteria

  • Pregnant women;
  • Unstable angina;
  • Class II, III or IV heart failure;
  • Recent cardiovascular event (last 3 months);
  • Chronic renal insufficiency;
  • Diabetes;
  • History of malignant diseases with life expectancy \<2 years;
  • Or Orthopedic limitations or any physical or mental limitation that impedes the performance of physical exercises.

Outcomes

Primary Outcomes

blood pressure

Time Frame: 48 hours

Blood pressure will be evaluated by Ambulatory Blood Pressure Monitoring (ABPM) over 24h. For that, a Dyna-Map® branded instrument will be used, which will measure blood pressure on rest condition and another measure after the exercise session (totaling 48 horas), in all participants of the two study groups.

Study Sites (1)

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