Acute Effect of Isometric Physical Exercise on Blood Pressure in Patients With Controlled Hypertension
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- blood pressure
研究概览
简要总结
International recommendations advocate dynamic or isometric strength training as an adjunct to aerobic exercise. Due to a lack of consensus, this research addresses the acute effects of isometric exercises by handgrip or lower limb isometry as a hypotensive strategy in hypertensive adults.
详细描述
This study is characterized as a randomized, controlled and blinded clinical trial for the evaluators and carried out integrally in the Laboratory of Clinical Investigation (LIC) of the Cardiology Institute of Rio Grande do Sul / University Foundation of Cardiology (ICFUC). The project follows all recommendations proposed by the CONSORT Statement.
The study will consist of individuals of both genders, aged between 40 and 70 years who have blood pressure above 120mmhg by 80mhg. The participants, after signing the informed consent, answered a questionnaire that will evaluate the habitual level of physical activity and will be submitted to isometric exercises of palmar grip or quadriceps muscle. Pre- and post-exercise blood pressure will be monitored through the ambulatory blood pressure monitoring (ABPM) method.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Controlled hypertensive patients (use of medication) sedentary or physically inactive
排除标准
- •Pregnant women;
- •Unstable angina;
- •Class II, III or IV heart failure;
- •Recent cardiovascular event (last 3 months);
- •Chronic renal insufficiency;
- •Diabetes;
- •History of malignant diseases with life expectancy <2 years;
- •Or Orthopedic limitations or any physical or mental limitation that impedes the performance of physical exercises.
结局指标
主要结局
blood pressure
时间窗: 48 hours
Blood pressure will be evaluated by Ambulatory Blood Pressure Monitoring (ABPM) over 24h. For that, a Dyna-Map® branded instrument will be used, which will measure blood pressure on rest condition and another measure after the exercise session (totaling 48 horas), in all participants of the two study groups.
次要结局
未报告次要终点
研究者
Patricia Caetano
principal investigador
Instituto de Cardiologia do Rio Grande do Sul