To test the levels of Lactate Dehydrogenase and study structure of red blood cells in patients with Oral submucous fibrosis and healthy individuals.

Not Applicable

• Conditions: Health Condition 1: K135- Oral submucous fibrosis

• Registration Number: CTRI/2023/08/056287
• Lead Sponsor: MGM Dental College And Hospital, Navi Mumbai.

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 August 2023

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Study group

-Clinically diagnosed cases of Oral submucous fibrosis

-Patientâ??s willingness to participate.

control group

-Healthy Individuals without any known medical history.

-Age, BMI, gender matched healthy individuals similar to

study group.

-Patients who are willing to participate.

Exclusion Criteria

Study group

-Patient with a history of known heart diseases. (myocardial

infarction)

-Patients on drugs therapy like procainamides. Patients with

history of consumption of aspirin, narcotics or alcohol.

-Patients suffering from arrhythmia, pulmonary infarction

and stroke or under their treatment. Patients suffering

from hepatitis, hypothyroidism, lung disease, liver disease,

kidney disease, pancreatitis, muscle trauma, and muscular

dystrophy.

-Patient not willing to participate in the study.

control group

-Patient with a history of known heart diseases. (myocardial

infarction)

-Patients on drugs therapy like procainamides. Patients with

history of consumption of aspirin, narcotics or alcohol.

-Patients suffering from arrhythmia, pulmonary infarction

and stroke or under their treatment. Patients suffering from

hepatitis, hypothyroidism, lung disease, liver disease,

kidney disease, pancreatitis, muscle trauma, and muscular

dystrophy.

-Patient not willing to participate in the study.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. To evaluate & compare the serum Lactate Dehydrogenase level in clinically diagnosed Oral submucous fibrosis & healthy individuals. <br/ ><br>2. To evaluate & compare morphometric characteristics of circulating RBCs in peripheral blood smear of clinically diagnosed Oral submucous fibrosis and healthy individuals. <br/ ><br> <br/ ><br>Timepoint: At the time of patient presentation, blood sample will be collected.

Secondary Outcome Measures

Name	Time	Method
To evaluate & compare the serum Lactate Dehydrogenase level and morphometric characteristics of circulating RBCs in peripheral blood smear among different clinical stages of clinically diagnosed Oral submucous fibrosis.Timepoint: at the time of patient presentation, blood sample will be collected.